HELPY:CATA

Species (Taxon ID)	Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacterpylori). (85962)
Gene Name(s)	katA
Protein Name(s)	Catalase
External Links
UniProt	P77872
EMBL	U67458 Z70679 AE000511
PIR	C64629
RefSeq	NP_207669.1 YP_006934789.1
PDB	1QWL 1QWM 2A9E 2IQF
PDBsum	1QWL 1QWM 2A9E 2IQF
ProteinModelPortal	P77872
SMR	P77872
DIP	DIP-3559N
IntAct	P77872
MINT	MINT-165967
STRING	85962.HP0875
PRIDE	P77872
EnsemblBacteria	AAD07923
GeneID	13870059 899404
KEGG	heo:C694_04480 hpy:HP0875
PATRIC	20593039
eggNOG	COG0753
KO	K03781
OMA	WDYRADD
OrthoDB	EOG6P5Z9F
SABIO-RK	P77872
EvolutionaryTrace	P77872
Proteomes	UP000000429
GO	GO:0005737 GO:0004096 GO:0020037 GO:0046872 GO:0042744
Gene3D	2.40.180.10
InterPro	IPR018028 IPR020835 IPR024708 IPR024711 IPR011614 IPR002226 IPR010582
PANTHER	PTHR11465
Pfam	PF00199 PF06628
PIRSF	PIRSF038928
PRINTS	PR00067
SMART	SM01060
SUPFAM	SSF56634
PROSITE	PS00437 PS00438 PS51402

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
	GO:0042744	hydrogen peroxide catabolic process	PMID:8955320	ECO:0000315			P		Under Results, section "Construction and characterization of catalase-deficient H. pylori mutant strains by transposon shuttle mutagenesis": The insertional inactivation of the chromosomal katA gene completely abolished catalase activity, which was measured by the disappearance of hydrogen peroxide. The wild-type strain (which contained katA but lacked known catalases) produced a high level of specific catalase activity (4,422 U/mg), but the katA mutant revealed only background activity (5 U/mg).	complete CACAO 6212
involved_in	GO:0042744	hydrogen peroxide catabolic process	PMID:8955320	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0042744	hydrogen peroxide catabolic process		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:88271 PANTHER:PTN000157250 PomBase:SPCC757.07c RGD:2279 SGD:S000002664 TAIR:locus:2034428 UniProtKB:O13289 UniProtKB:P04040 UniProtKB:P77872 UniProtKB:Q42547 dictyBase:DDB_G0274595	P		Seeded From UniProt	complete
involved_in	GO:0042542	response to hydrogen peroxide		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0000261 PANTHER:PTN000157250 TAIR:locus:2034428 UniProtKB:O13289 UniProtKB:Q59635	P		Seeded From UniProt	complete
enables	GO:0020037	heme binding		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000157250 UniProtKB:P04040	F		Seeded From UniProt	complete
enables	GO:0004096	catalase activity		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0000261 MGI:MGI:88271 PANTHER:PTN000157250 PomBase:SPCC757.07c RGD:2279 SGD:S000002664 SGD:S000003320 UniProtKB:O13289 UniProtKB:O52762 UniProtKB:P00432 UniProtKB:P04040 UniProtKB:P12365 UniProtKB:P18122 UniProtKB:P18123 UniProtKB:P25819 UniProtKB:Q59337 UniProtKB:Q5B0L2 WB:WBGene00000830 WB:WBGene00000831 dictyBase:DDB_G0274595	F		Seeded From UniProt	complete
involved_in	GO:0098869	cellular oxidant detoxification	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0004096	P		Seeded From UniProt	complete
involved_in	GO:0098869	cellular oxidant detoxification	GO_REF:0000108	ECO:0000364	evidence based on logical inference from manual annotation used in automatic assertion	GO:0004096	P		Seeded From UniProt	complete
involved_in	GO:0098869	cellular oxidant detoxification	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0004601	P		Seeded From UniProt	complete
involved_in	GO:0098869	cellular oxidant detoxification	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0004096	P		Seeded From UniProt	complete
enables	GO:0004096	catalase activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR011614 InterPro:IPR018028 InterPro:IPR024708 InterPro:IPR024711 InterPro:IPR037060 InterPro:IPR040333	F		Seeded From UniProt	complete
involved_in	GO:0006979	response to oxidative stress	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR018028 InterPro:IPR024711 InterPro:IPR040333	P		Seeded From UniProt	complete
enables	GO:0020037	heme binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR002226 InterPro:IPR011614 InterPro:IPR018028 InterPro:IPR020835 InterPro:IPR024711 InterPro:IPR037060 InterPro:IPR040333	F		Seeded From UniProt	complete
involved_in	GO:0042744	hydrogen peroxide catabolic process	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR040333	P		Seeded From UniProt	complete
involved_in	GO:0055114	oxidation-reduction process	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR011614 InterPro:IPR018028 InterPro:IPR020835 InterPro:IPR024711 InterPro:IPR037060	P		Seeded From UniProt	complete
enables	GO:0004096	catalase activity	GO_REF:0000003	ECO:0000501	evidence used in automatic assertion	EC:1.11.1.6	F		Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0963 UniProtKB-SubCell:SL-0086	C		Seeded From UniProt	complete
enables	GO:0046872	metal ion binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0479	F		Seeded From UniProt	complete
enables	GO:0004601	peroxidase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0575	F		Seeded From UniProt	complete
involved_in	GO:0055114	oxidation-reduction process	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0560	P		Seeded From UniProt	complete
involved_in	GO:0042744	hydrogen peroxide catabolic process	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0376	P		Seeded From UniProt	complete
enables	GO:0016491	oxidoreductase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0560	F		Seeded From UniProt	complete
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References

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