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HELPX:Q6UK76

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Species (Taxon ID) Helicobacter pylori (Campylobacter pylori). (210)
Gene Name(s) ureB (ECO:0000313 with EMBL:AAR89367.1)
Protein Name(s) UreB (ECO:0000313 with EMBL:AAR89367.1)
External Links
UniProt Q6UK76
EMBL AY368262
ProteinModelPortal Q6UK76
GO GO:0016151
GO:0009039
GO:0009405
GO:0043419
Gene3D 2.30.40.10
InterPro IPR006680
IPR011059
IPR011612
IPR017951
IPR029754
Pfam PF01979
PF00449
SUPFAM SSF51338
PROSITE PS01120
PS51368

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0009405

pathogenesis

PMID:8039935[1]

ECO:0000315

P

Table 1. Shows that strain HPT73, transformed by plasmid pHPT54 that includes a disruption of ureB gene by kanamycin resistance determinant insertion, had significantly reduced ability to colonize nude mouse stomach.

complete
CACAO 5352

involved_in

GO:0009405

pathogenesis

PMID:8039935[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0006807

nitrogen compound metabolic process

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR005848
InterPro:IPR017951

P

Seeded From UniProt

complete

enables

GO:0009039

urease activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR005848
InterPro:IPR017951

F

Seeded From UniProt

complete

enables

GO:0016151

nickel cation binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR005848
InterPro:IPR017951
InterPro:IPR029754

F

Seeded From UniProt

complete

enables

GO:0016787

hydrolase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR006680

F

Seeded From UniProt

complete

enables

GO:0016810

hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR011059

F

Seeded From UniProt

complete

enables

GO:0009039

urease activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:3.5.1.5

F

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0963

C

Seeded From UniProt

complete

enables

GO:0016787

hydrolase activity

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0378

F

Seeded From UniProt

complete

enables

GO:0046872

metal ion binding

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0479

F

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000040

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-SubCell:SL-0086

C

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000415999

C

Seeded From UniProt

complete

involved_in

GO:0043419

urea catabolic process

GO_REF:0000041

ECO:0000322

imported manually asserted information used in automatic assertion

UniPathway:UPA00258

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Tsuda, M et al. (1994) A urease-negative mutant of Helicobacter pylori constructed by allelic exchange mutagenesis lacks the ability to colonize the nude mouse stomach. Infect. Immun. 62 3586-9 PubMed GONUTS page