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HCMVM:GO

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Species (Taxon ID) Human cytomegalovirus (strain Merlin) (HHV-5) (Human herpesvirus 5). (295027)
Gene Name(s) UL74
Protein Name(s) Envelope glycoprotein O
External Links
UniProt F5HGP1
EMBL AY446894
RefSeq YP_081522.1
GeneID 3077572
Proteomes UP000000938
GO GO:0019031
GO:0055036
GO:0046597
InterPro IPR012564
Pfam PF07982

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0046597

negative regulation of viral entry into host cell

PMID:21880752[1]

ECO:0000315

P

The coexpression of gO with gH/gL substantially increases interference in human fibroblasts compared with gH/gL alone and that gH/gL/gO does not interfere in epithelial cells. Evidence for this claim is demonstrated in Figure 1.

complete
CACAO 6568

involved_in

GO:0046597

negative regulation of viral entry into host cell

PMID:21880752[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0019012

virion

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0946

C

Seeded From UniProt

complete

part_of

GO:0019031

viral envelope

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0261

C

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0472

C

Seeded From UniProt

complete

part_of

GO:0055036

virion membrane

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0275

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Vanarsdall, AL et al. (2011) Human cytomegalovirus glycoprotein gO complexes with gH/gL, promoting interference with viral entry into human fibroblasts but not entry into epithelial cells. J. Virol. 85 11638-45 PubMed GONUTS page