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HALVD:D4GQN4

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Species (Taxon ID) Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC14742 / NCIMB 2012 / VKM B-1768 / DS2) (Halobacterium volcanii). (309800)
Gene Name(s) cas6 (ECO:0000313 with EMBL:ADE01675.1)
Protein Name(s) CRISPR-associated protein Cas6 (ECO:0000313 with EMBL:ADE01675.1)
External Links
UniProt D4GQN4
EMBL CP001955
RefSeq WP_013035014.1
YP_003533663.1
EnsemblBacteria ADE01675
GeneID 8923584
KEGG hvo:HVO_A0205
HOGENOM HOG000092591
OMA NIGEMPF
BioCyc HVOL309800:GCOK-3226-MONOMER
Proteomes UP000008243

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0043571

maintenance of CRISPR repeat elements

PMID:24459147[1]

ECO:0000315

P

Figure 6 shows that a cas6 deletion mutant cannot generate crRNA.

complete
CACAO 10030

involved_in

GO:0090305

nucleic acid phosphodiester bond hydrolysis

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0004519

P

Seeded From UniProt

complete

involved_in

GO:0090305

nucleic acid phosphodiester bond hydrolysis

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0004518

P

Seeded From UniProt

complete

enables

GO:0016788

hydrolase activity, acting on ester bonds

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR010156

F

Seeded From UniProt

complete

enables

GO:0003723

RNA binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0694

F

Seeded From UniProt

complete

enables

GO:0016787

hydrolase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0378

F

Seeded From UniProt

complete

enables

GO:0004519

endonuclease activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0255

F

Seeded From UniProt

complete

enables

GO:0004518

nuclease activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0540

F

Seeded From UniProt

complete

involved_in

GO:0051607

defense response to virus

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0051

P

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0963
UniProtKB-SubCell:SL-0086

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Brendel, J et al. (2014) A complex of Cas proteins 5, 6, and 7 is required for the biogenesis and stability of clustered regularly interspaced short palindromic repeats (crispr)-derived rnas (crrnas) in Haloferax volcanii. J. Biol. Chem. 289 7164-77 PubMed GONUTS page