GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.
HAEIF:LIC2B
Contents
| Species (Taxon ID) | Haemophilus influenzae. (727) | |
| Gene Name(s) | lic2B | |
| Protein Name(s) | Lipooligosaccharide biosynthesis protein lic2B | |
| External Links | ||
| UniProt | Q57394 | |
| EMBL | Z54182 U36398 | |
| PIR | S71025 | |
| CAZy | GT25 | |
| GO | GO:0016757 GO:0009103 GO:0009405 | |
| InterPro | IPR002654 | |
| Pfam | PF01755 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
| GO:0016757 |
transferase activity, transferring glycosyl groups |
ECO:0000315 |
F |
Table 3&4. Examination of carbohydrate modification by negative-ion CE-ES-MS. Comparison of lic2B mutant to wildtype reveals structural dissimilarities. Sugar composition analysis indicated that the lic2B mutant LOS was devoid of galactose in its outer core, in contrast to that of the wildtype. |
complete | |||||
| GO:0009103 |
lipopolysaccharide biosynthetic process |
ECO:0000255 |
UniProtKB: |
P |
Figure 3: with two independently derived clones for each mutation, lic2B and lic2C mutants yielded marked and statistically significant decreases in survival compared to the wild type |
complete | ||||
|
enables |
GO:0016757 |
transferase activity, transferring glycosyl groups |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016740 |
transferase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016757 |
transferase activity, transferring glycosyl groups |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0009405 |
pathogenesis |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 Wong, SM et al. (2011) ArcA-regulated glycosyltransferase lic2B promotes complement evasion and pathogenesis of nontypeable Haemophilus influenzae. Infect. Immun. 79 1971-83 PubMed GONUTS page
