HAEI8:VAPC1

Species (Taxon ID)	Haemophilus influenzae (strain 86-028NP). (281310)
Gene Name(s)	vapC1 (ECO:0000255 with HAMAP-Rule:MF_00265)
Protein Name(s)	Ribonuclease VapC1 (ECO:0000255 with HAMAP-Rule:MF_00265) RNase VapC (ECO:0000255 with HAMAP-Rule:MF_00265) Toxin VapC (ECO:0000255 with HAMAP-Rule:MF_00265)
External Links
UniProt	Q4QNL7
EMBL	CP000057
RefSeq	YP_248040.1
ProteinModelPortal	Q4QNL7
STRING	281310.NTHI0440
EnsemblBacteria	AAX87380
GeneID	3429761
KEGG	hit:NTHI0440
PATRIC	20181055
eggNOG	COG1487
HOGENOM	HOG000121274
KO	K07062
OMA	VIWHYGE
OrthoDB	EOG6ZWJH4
BioCyc	HINF281310:GJ89-413-MONOMER
Proteomes	UP000002525
GO	GO:0000287 GO:0004540 GO:0090501
Gene3D	3.40.50.1010
HAMAP	MF_00265
InterPro	IPR002716 IPR029060 IPR022907
Pfam	PF01850
SMART	SM00670
SUPFAM	SSF88723

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
	GO:0004540	ribonuclease activity	PMID:17496075	ECO:0000314			F		Figure 7A. Total RNA from E. coli K-12 or H. influenzae strain 86-028NP was used as the substrate in RNase activity assays with increasing amounts of the purified VapC-1 toxin. As shown, RNA bands diminish with increasing VapC-1 concentration.	complete CACAO 6003
enables	GO:0004540	ribonuclease activity	PMID:17496075	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
involved_in	GO:0090305	nucleic acid phosphodiester bond hydrolysis	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0004518	P		Seeded From UniProt	complete
involved_in	GO:0090501	RNA phosphodiester bond hydrolysis	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0004540	P		Seeded From UniProt	complete
involved_in	GO:0090501	RNA phosphodiester bond hydrolysis	GO_REF:0000108	ECO:0000364	evidence based on logical inference from manual annotation used in automatic assertion	GO:0004540	P		Seeded From UniProt	complete
enables	GO:0004540	ribonuclease activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR022907	F		Seeded From UniProt	complete
enables	GO:0000287	magnesium ion binding	GO_REF:0000104	ECO:0000256	match to sequence model evidence used in automatic assertion	UniRule:UR000083071	F		Seeded From UniProt	complete
enables	GO:0016787	hydrolase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0378	F		Seeded From UniProt	complete
enables	GO:0004518	nuclease activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0540	F		Seeded From UniProt	complete
enables	GO:0046872	metal ion binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0479	F		Seeded From UniProt	complete
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References

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