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HAEI8:Q4QNP7

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Species (Taxon ID) Haemophilus influenzae (strain 86-028NP). (281310)
Gene Name(s) pilD (ECO:0000313 with EMBL:AAX87350.1)
Protein Name(s) Putative type 4 prepilin-like protein specific leader peptidase (ECO:0000313 with EMBL:AAX87350.1)
External Links
UniProt Q4QNP7
EMBL CP000057
RefSeq WP_011271970.1
YP_248010.1
STRING 281310.NTHI0406
EnsemblBacteria AAX87350
GeneID 3429730
KEGG hit:NTHI0406
PATRIC 20180987
eggNOG COG1989
HOGENOM HOG000286087
KO K02506
OMA CGHILRY
OrthoDB EOG69D3BR
BioCyc HINF281310:GJ89-382-MONOMER
Proteomes UP000002525
GO GO:0016020
GO:0004190
GO:0042710
GO:0052001
InterPro IPR000045
Pfam PF01478

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:1900231

regulation of single-species biofilm formation on inanimate substrate

PMID:22328674[1]

ECO:0000315

P

Figure 2A&B. NTHI pilD mutants had significantly reduced biofilm thickness and biomass compared to the wildtype.

complete
CACAO 5964

GO:0052001

Type IV pili-dependent localized adherence to host

PMID:22328674[1]

ECO:0000315

P

Figure 3. NTHI pilD mutants had significant adherence defects on normal human bronchial epithelial cells compared to the wildtype.

complete
CACAO 5965

involved_in

GO:1900231

regulation of single-species biofilm formation on inanimate substrate

PMID:22328674[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0052001

type IV pili-dependent localized adherence to host

PMID:22328674[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0006508

proteolysis

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0004190

P

Seeded From UniProt

complete

enables

GO:0004190

aspartic-type endopeptidase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000045

F

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000045

C

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0472

C

Seeded From UniProt

complete

part_of

GO:0016021

integral component of membrane

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0812

C

Seeded From UniProt

complete

enables

GO:0016787

hydrolase activity

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0378

F

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 1.3 Carruthers, MD et al. (2012) Biological roles of nontypeable Haemophilus influenzae type IV pilus proteins encoded by the pil and com operons. J. Bacteriol. 194 1927-33 PubMed GONUTS page