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HAEI8:MURA
Contents
Species (Taxon ID) | Haemophilus influenzae (strain 86-028NP). (281310) | |
Gene Name(s) | murA (ECO:0000255 with HAMAP-Rule:MF_00111) | |
Protein Name(s) | UDP-N-acetylglucosamine 1-carboxyvinyltransferase (ECO:0000255 with HAMAP-Rule:MF_00111)
Enoylpyruvate transferase (ECO:0000255 with HAMAP-Rule:MF_00111) UDP-N-acetylglucosamine enolpyruvyl transferase (ECO:0000255 with HAMAP-Rule:MF_00111) EPT (ECO:0000255 with HAMAP-Rule:MF_00111) | |
External Links | ||
UniProt | Q4QLK7 | |
EMBL | CP000057 | |
RefSeq | YP_248750.1 | |
ProteinModelPortal | Q4QLK7 | |
SMR | Q4QLK7 | |
STRING | 281310.NTHI1244 | |
BindingDB | Q4QLK7 | |
EnsemblBacteria | AAX88090 | |
GeneID | 3430516 | |
KEGG | hit:NTHI1244 | |
PATRIC | 20182611 | |
eggNOG | COG0766 | |
HOGENOM | HOG000075602 | |
KO | K00790 | |
OMA | IRTAPHP | |
OrthoDB | EOG68M4GK | |
BioCyc | HINF281310:GJ89-1168-MONOMER | |
UniPathway | UPA00219 | |
Proteomes | UP000002525 | |
GO | GO:0005737 GO:0008760 GO:0007049 GO:0051301 GO:0071555 GO:0009252 GO:0008360 GO:0019277 | |
Gene3D | 3.65.10.10 | |
HAMAP | MF_00111 | |
InterPro | IPR001986 IPR013792 IPR005750 | |
PANTHER | PTHR21090:SF4 | |
Pfam | PF00275 | |
SUPFAM | SSF55205 | |
TIGRFAMs | TIGR01072 |
Annotations
Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
---|---|---|---|---|---|---|---|---|---|---|
GO:0008760 |
UDP-N-acetylglucosamine 1-carboxyvinyltransferase activity |
ECO:0000315 |
F |
Figure 3 demonstrates the inhibitory activities on MurA and then determines the residual activity. Figure 5 demonstrates the inhibitory actions of sulfhydryl group dependent activity on the mutant phenotype. |
complete | |||||
enables |
GO:0008760 |
UDP-N-acetylglucosamine 1-carboxyvinyltransferase activity |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0003824 |
catalytic activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0008760 |
UDP-N-acetylglucosamine 1-carboxyvinyltransferase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0016765 |
transferase activity, transferring alkyl or aryl (other than methyl) groups |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0019277 |
UDP-N-acetylgalactosamine biosynthetic process |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
enables |
GO:0008760 |
UDP-N-acetylglucosamine 1-carboxyvinyltransferase activity |
ECO:0000501 |
evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0008760 |
UDP-N-acetylglucosamine 1-carboxyvinyltransferase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000001460 |
F |
Seeded From UniProt |
complete | ||
part_of |
GO:0005737 |
cytoplasm |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000001460 |
C |
Seeded From UniProt |
complete | ||
involved_in |
GO:0009252 |
peptidoglycan biosynthetic process |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000001460 |
P |
Seeded From UniProt |
complete | ||
enables |
GO:0016740 |
transferase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0071555 |
cell wall organization |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
part_of |
GO:0005737 |
cytoplasm |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
involved_in |
GO:0008360 |
regulation of cell shape |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0007049 |
cell cycle |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0051301 |
cell division |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0009252 |
peptidoglycan biosynthetic process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
UniProtKB-KW:KW-0573 |
P |
Seeded From UniProt |
complete | ||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Han, SG et al. (2013) Identification of novel irreversible inhibitors of UDP-N-acetylglucosamine enolpyruvyl transferase (MurA) from Haemophilus influenzae. J. Microbiol. Biotechnol. 23 329-34 PubMed GONUTS page