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HAEDU:Q93Q08
Contents
| Species (Taxon ID) | Haemophilus ducreyi. (730) | |
| Gene Name(s) | lspA2 (ECO:0000313 with EMBL:AAK83078.1) | |
| Protein Name(s) | Large supernatant protein 2 LspA2 (ECO:0000313 with EMBL:AAK83078.1) | |
| External Links | ||
| UniProt | Q93Q08 | |
| EMBL | AF289079 | |
| ProteinModelPortal | Q93Q08 | |
| Gene3D | 2.160.20.10 | |
| InterPro | IPR024973 IPR008638 IPR012334 IPR011050 | |
| Pfam | PF13018 PF05860 | |
| SUPFAM | SSF51126 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
| GO:0009405 |
pathogenesis |
ECO:0000315 |
P |
Table 2. In rabbit model, the lspA2 mutant yielded lesion scores that were lower than those obtained with the wild-type parent strain. While these differences were modest, they were nonetheless significant. |
complete | |||||
| GO:0050765 |
negative regulation of phagocytosis |
ECO:0000315 |
P |
Enables resistance to phagocytosis along with LspA1. Figure 5. The lspA1 lspA2 mutant lost ability to resist phagocytosis. |
complete | |||||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Ward, CK et al. (2003) Mutations in the lspA1 and lspA2 genes of Haemophilus ducreyi affect the virulence of this pathogen in an animal model system. Infect. Immun. 71 2478-86 PubMed GONUTS page
- ↑ Vakevainen, M et al. (2003) Inhibition of phagocytosis by Haemophilus ducreyi requires expression of the LspA1 and LspA2 proteins. Infect. Immun. 71 5994-6003 PubMed GONUTS page
