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HAEDC:Q9ZHL3

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Species (Taxon ID) Haemophilus ducreyi. (730)
Gene Name(s) lspA1 (ECO:0000313 with EMBL:AAC79757.1)
Protein Name(s) Large supernatant protein 1 (ECO:0000313 with EMBL:AAC79757.1)
External Links
UniProt Q9ZHL3
EMBL AF057695
PIR T31102
ProteinModelPortal Q9ZHL3
GO GO:0004197
GO:0009405
Gene3D 2.160.20.10
InterPro IPR024973
IPR008619
IPR008638
IPR025157
IPR012334
IPR011050
IPR006473
Pfam PF13018
PF05594
PF13332
PF05860
PF03543
SMART SM00912
SUPFAM SSF51126
TIGRFAMs TIGR01901
TIGR01586

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0009405

pathogenesis

PMID:14500520[1]

ECO:0000315

P

Fig 5 shows the resistance to phagocytosis of wild-type and mutant strains of H. ducreyi. The wild-type strain is resistant to phagocytosis.

complete

GO:0020012

evasion or tolerance of host immune response

PMID:14500520[1]

ECO:0000315

P

Figures 1 and 2 show the ability of the LspA1 mutant to inhibit the phagocytic activity of HL-60 and U-937, respectively. The LspA1 mutant, shown in column 3, is very like the wild type (column 1).

complete
CACAO 5350

involved_in

GO:0006508

proteolysis

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0004197

P

Seeded From UniProt

complete

enables

GO:0004197

cysteine-type endopeptidase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR006473

F

Seeded From UniProt

complete

involved_in

GO:0009405

pathogenesis

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR006473

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Vakevainen, M et al. (2003) Inhibition of phagocytosis by Haemophilus ducreyi requires expression of the LspA1 and LspA2 proteins. Infect. Immun. 71 5994-6003 PubMed GONUTS page