HAEDC:Q9K2H6

Species (Taxon ID)	Haemophilus ducreyi. (730)
Gene Name(s)	dsrA (ECO:0000313 with EMBL:AAF37813.1)
Protein Name(s)	Serum resistance protein DsrA (ECO:0000313 with EMBL:AAF37813.1)
External Links
UniProt	Q9K2H6
EMBL	AF187001 AF187005 AF187007
ProteinModelPortal	Q9K2H6
STRING	233412.HD0769
PATRIC	20177953
GO	GO:0009279 GO:0020012 GO:0009405
InterPro	IPR005594
Pfam	PF03895

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
	GO:0009405	pathogenesis	PMID:11179317	ECO:0000315			P		Tables 1 and 2 show the results of inoculation with wild-type and DsrA mutant H. ducreyi. Table 1 shows that the mutant is impaired in its ability to cause papules. Table 2 shows that the mutant (at an increased dose) forms smaller papules than the wild-type, on par with the heat-inactivated wild-type.	complete CACAO 5378
	GO:0009279	cell outer membrane	PMID:10678980	ECO:0000314			C		Fig 5 shows the SDS-PAGE and Western blot identifying DsrA. Figure caption includes details about preparation of outer membrane for experiment.	complete CACAO 5151
	GO:0020012	evasion or tolerance of host immune response	PMID:10678980	ECO:0000315			P		Figure 6 shows that the DsrA mutant has lower resistance to bactericidal killing than the wild-type organism. Figure 7 shows that complementation of the mutant restores resistance	complete CACAO 5379
involved_in	GO:0020012	evasion or tolerance of host immune response	PMID:10678980	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0009405	pathogenesis	PMID:11179317	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0009279	cell outer membrane	PMID:10678980	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
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References

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