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HAEDC:Q58ZK4

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Species (Taxon ID) Haemophilus ducreyi. (730)
Gene Name(s) ncaA (ECO:0000313 with EMBL:AAU12595.1)
Protein Name(s) Necessary for collagen adhesion A1 (ECO:0000313 with EMBL:AAU12597.1)

Necessary for collagen adhesion A2 (ECO:0000313 with EMBL:AAU12595.1)

External Links
UniProt Q58ZK4
EMBL AY606128
AY606129
AY612645
AY612646
AY612647
ProteinModelPortal Q58ZK4
GO GO:0009279
GO:0005581
GO:0009405
InterPro IPR005594
Pfam PF03895

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0009279

cell outer membrane

PMID:16622201[1]

ECO:0000314

C

The materials and methods section entitled "Radioimmunoprecipitation of H. ducreyi outer membrane proteins" describes the process used to isolate the outer membrane proteins.

complete
CACAO 5384

GO:0009405

pathogenesis

PMID:16622201[1]

ECO:0000315

P

Tables 1 and 2 show the results of inoculation of wild-type and ncaA mutant H. ducreyi. The mutant had decreased virulence in the swine (table 1) and human (table 2) models of infection compared to the wild-type.

complete
CACAO 5385

involved_in

GO:0009405

pathogenesis

PMID:16622201[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0009279

cell outer membrane

PMID:16622201[1]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 1.3 Fulcher, RA et al. (2006) Expression of Haemophilus ducreyi collagen binding outer membrane protein NcaA is required for virulence in swine and human challenge models of chancroid. Infect. Immun. 74 2651-8 PubMed GONUTS page