GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.
GRARO:WGRTX
Contents
| Species (Taxon ID) | Grammostola rosea (Chilean rose tarantula) (Grammostola spatulata). (432528) | |
| Gene Name(s) | No Information Provided. | |
| Protein Name(s) | Omega-theraphotoxin-Gr1a
Omega-TRTX-Gr1a Omega-GTX SIA Omega-GsTx SIA Omega-grammotoxin SIA Omega-GrTx SIA | |
| External Links | ||
| UniProt | P60590 | |
| EMBL | AB612243 | |
| PDB | 1KOZ | |
| PDBsum | 1KOZ | |
| TCDB | 8.B.5.3.7 | |
| ArachnoServer | AS000426 | |
| EvolutionaryTrace | P60590 | |
| GO | GO:0005576 GO:0008200 GO:0009405 | |
| InterPro | IPR011696 | |
| Pfam | PF07740 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
| GO:0019855 |
calcium channel inhibitor activity |
ECO:0000314 |
F |
Fig. 1 |
complete | |||||
| GO:0019870 |
potassium channel inhibitor activity |
ECO:0000314 |
F |
Fig. 2 |
complete | |||||
|
enables |
GO:0019870 |
potassium channel inhibitor activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0019855 |
calcium channel inhibitor activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005576 |
extracellular region |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0008200 |
ion channel inhibitor activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0009405 |
pathogenesis |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0090729 |
toxin activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005576 |
extracellular region |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 McDonough, SI et al. (1997) Voltage-dependent inhibition of N- and P-type calcium channels by the peptide toxin omega-grammotoxin-SIA. Mol. Pharmacol. 52 1095-104 PubMed GONUTS page
- ↑ 2.0 2.1 Li-Smerin, Y & Swartz, KJ (1998) Gating modifier toxins reveal a conserved structural motif in voltage-gated Ca2+ and K+ channels. Proc. Natl. Acad. Sci. U.S.A. 95 8585-9 PubMed GONUTS page
