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GEOMG:Q39Q67

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Species (Taxon ID) Geobacter metallireducens (strain GS-15 / ATCC 53774 / DSM 7210). (269799)
Gene Name(s) gabD (ECO:0000313 with EMBL:ABB33607.2)
Protein Name(s) 4-oxobutanoate dehydrogenase (ECO:0000313 with EMBL:ABB33607.2)
External Links
UniProt Q39Q67
EMBL CP000148
RefSeq WP_004512621.1
ProteinModelPortal Q39Q67
STRING 269799.Gmet_3395
EnsemblBacteria ABB33607
KEGG gme:Gmet_3395
eggNOG ENOG4105C26
COG1012
HOGENOM HOG000271509
KO K00135
OMA NSFVEWF
OrthoDB 384611at2
Proteomes UP000007073
GO GO:0009013
GO:0009450
Gene3D 3.40.309.10
3.40.605.10
InterPro IPR016161
IPR016163
IPR016160
IPR029510
IPR016162
IPR015590
IPR010102
Pfam PF00171
SUPFAM SSF53720
TIGRFAMs TIGR01780
PROSITE PS00070
PS00687

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0009013

succinate-semialdehyde dehydrogenase [NAD(P)+] activity

PMID:22037946[1]

ECO:0000314

direct assay evidence used in manual assertion

F

Figure 3 shows the succinic semialdehyde reducing ability to reducing SSA and demonstrated that NADPH/NADP+ is the suitable co-factor for these enzymes.

complete
CACAO 8978

GO:0009013

succinate-semialdehyde dehydrogenase [NAD(P)+] activity

PMID:22037946[1]

ECO:0000247

sequence alignment evidence used in manual assertion

PMID:10320398[2]


F

Table 4 shows the similarities in sequence between the SSAR proteins from Geobacter sulfurreducens and Geobacter metallireducens as compared to Arabidopsis thaliana, showing 64% sequence similarity

complete
CACAO 8979

enables

GO:0009013

succinate-semialdehyde dehydrogenase [NAD(P)+] activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR010102

F

Seeded From UniProt

complete

involved_in

GO:0009450

gamma-aminobutyric acid catabolic process

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR010102

P

Seeded From UniProt

complete

enables

GO:0016491

oxidoreductase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR015590
InterPro:IPR016160
InterPro:IPR016161
InterPro:IPR016162
InterPro:IPR016163
InterPro:IPR029510

F

Seeded From UniProt

complete

enables

GO:0016620

oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR016163

F

Seeded From UniProt

complete

involved_in

GO:0055114

oxidation-reduction process

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR010102
InterPro:IPR015590
InterPro:IPR016160
InterPro:IPR016161
InterPro:IPR016162
InterPro:IPR016163
InterPro:IPR029510

P

Seeded From UniProt

complete

involved_in

GO:0055114

oxidation-reduction process

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0560

P

Seeded From UniProt

complete

enables

GO:0016491

oxidoreductase activity

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0560

F

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Zhang, Y et al. (2011) Identification of succinic semialdehyde reductases from Geobacter: expression, purification, crystallization, preliminary functional, and crystallographic analysis. Acta Biochim. Biophys. Sin. (Shanghai) 43 996-1002 PubMed GONUTS page
  2. Gouet, P et al. (1999) ESPript: analysis of multiple sequence alignments in PostScript. Bioinformatics 15 305-8 PubMed GONUTS page