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FRATL:Q7X168

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Species (Taxon ID) Francisella tularensis subsp. tularensis. (119856)
Gene Name(s) tul4 (ECO:0000313 with EMBL:AAO43577.1)
Protein Name(s) Tul4 membrane protein (ECO:0000313 with EMBL:AAO43577.1)
External Links
UniProt Q7X168
EMBL AY205301

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0002437

inflammatory response to antigenic stimulus

PMID:19233475[1]

ECO:0000314

P

Figure 6: Tul4 was recognized during acute infections - examined the F. tularensis specific IFNγ responses of mice after intradermal inoculation with tularensis LVS. Splenocytes were isolated and stimulated in vitro for 18–24 h with Tul4 86–99 peptide. Cells were then stained using an array of cellular markers followed by analysis via multicolor flow cytometry, which allowed for identification of activated IFNγ positive CD4+ T cells.

complete
CACAO 9074

Notes

References

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  1. Valentino, MD et al. (2009) Identification of a dominant CD4 T cell epitope in the membrane lipoprotein Tul4 from Francisella tularensis LVS. Mol. Immunol. 46 1830-8 PubMed GONUTS page