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ENTFL:Q6WRY5

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Species (Taxon ID) Enterococcus faecalis (Streptococcus faecalis). (1351)
Gene Name(s) vanG (ECO:0000313 with EMBL:AAQ16273.1) (synonyms: ddl (ECO:0000256 with HAMAP-Rule:MF_00047))
Protein Name(s) D-alanine--D-alanine ligase (ECO:0000256 with HAMAP-Rule:MF_00047)

D-Ala-D-Ala ligase (ECO:0000256 with HAMAP-Rule:MF_00047) D-alanylalanine synthetase (ECO:0000256 with HAMAP-Rule:MF_00047)

External Links
UniProt Q6WRY5
EMBL AY271782
DQ212986
PDB 4FU0
PDBsum 4FU0
BioCyc MetaCyc:MONOMER-15480
UniPathway UPA00219
GO GO:0005737
GO:0005524
GO:0008716
GO:0000287
GO:0030145
GO:0071555
GO:0009252
GO:0008360
Gene3D 3.30.1490.20
3.30.470.20
3.40.50.20
HAMAP MF_00047
InterPro IPR011761
IPR013815
IPR013816
IPR000291
IPR005905
IPR011095
IPR011127
IPR016185
Pfam PF07478
PF01820
PIRSF PIRSF039102
SUPFAM SSF52440
TIGRFAMs TIGR01205
PROSITE PS50975
PS00843
PS00844

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0008716

D-alanine-D-alanine ligase activity

PMID:22969085[1]

ECO:0000314

F

figure 2, part A, lane 2

complete
CACAO 11411

enables

GO:0005524

ATP binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR011761
InterPro:IPR013815

F

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR005905

C

Seeded From UniProt

complete

enables

GO:0008716

D-alanine-D-alanine ligase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR005905
InterPro:IPR011095

F

Seeded From UniProt

complete

enables

GO:0046872

metal ion binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR011761

F

Seeded From UniProt

complete

enables

GO:0008716

D-alanine-D-alanine ligase activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:6.3.2.4

F

Seeded From UniProt

complete

involved_in

GO:0008360

regulation of cell shape

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0133

P

Seeded From UniProt

complete

enables

GO:0016874

ligase activity

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0436

F

Seeded From UniProt

complete

enables

GO:0000166

nucleotide binding

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0547

F

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0963

C

Seeded From UniProt

complete

enables

GO:0005524

ATP binding

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0067

F

Seeded From UniProt

complete

enables

GO:0046872

metal ion binding

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0479

F

Seeded From UniProt

complete

involved_in

GO:0009252

peptidoglycan biosynthetic process

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0573

P

Seeded From UniProt

complete

involved_in

GO:0071555

cell wall organization

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0961

P

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000040

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-SubCell:SL-0086

C

Seeded From UniProt

complete

involved_in

GO:0009252

peptidoglycan biosynthetic process

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000001246

P

Seeded From UniProt

complete

enables

GO:0000166

nucleotide binding

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000414645

F

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000001246

C

Seeded From UniProt

complete

enables

GO:0008716

D-alanine-D-alanine ligase activity

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000001246

F

Seeded From UniProt

complete

enables

GO:0005524

ATP binding

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000414645

F

Seeded From UniProt

complete

involved_in

GO:0009252

peptidoglycan biosynthetic process

GO_REF:0000041

ECO:0000322

imported manually asserted information used in automatic assertion

UniPathway:UPA00219

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Meziane-Cherif, D et al. (2012) Structural and functional characterization of VanG D-Ala:D-Ser ligase associated with vancomycin resistance in Enterococcus faecalis. J. Biol. Chem. 287 37583-92 PubMed GONUTS page