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ENTFL:B1B1Z5

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Species (Taxon ID) Enterococcus faecalis (Streptococcus faecalis). (1351)
Gene Name(s) bacL1 (ECO:0000313 with EMBL:BAG12399.1)
Protein Name(s) Lysozyme (ECO:0000256 with RuleBase:RU003788)
External Links
UniProt B1B1Z5
EMBL AB271686
ProteinModelPortal B1B1Z5
CAZy GH24
MEROPS C40.014
GO GO:0003796
GO:0016998
GO:0019835
GO:0042742
GO:0009253
Gene3D 1.10.530.40
3.90.1720.10
InterPro IPR002196
IPR023346
IPR023347
IPR000064
IPR008044
IPR003646
Pfam PF05382
PF00959
PF08460
SUPFAM SSF53955

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0061786

peptidoglycan stem peptide endopeptidase activity

PMID:24235140[1]

ECO:0000314

F

Figure 5: To determine the BacL1 cleavage site, the soluble product generated from BacL1-treated peptidoglycan was separated by reverse-phase HPLC on an ODS-Hypersil column. The HPLC fractions were analyzed by MALDI-PSD analysis to determine their molecular structures. The data indicate that BacL1 has an endopeptidase activity that hydrolyzes the peptide bond between d-isoglutamine and l-lysine in the stem peptide.

complete
CACAO 12163

enables

GO:0003796

lysozyme activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR002196

F

Seeded From UniProt

complete

involved_in

GO:0009253

peptidoglycan catabolic process

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR002196

P

Seeded From UniProt

complete

involved_in

GO:0016998

cell wall macromolecule catabolic process

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR002196

P

Seeded From UniProt

complete

enables

GO:0003796

lysozyme activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:3.2.1.17

F

Seeded From UniProt

complete

involved_in

GO:0042742

defense response to bacterium

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0081

P

Seeded From UniProt

complete

enables

GO:0016787

hydrolase activity

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0378

F

Seeded From UniProt

complete

involved_in

GO:0008152

metabolic process

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0081

P

Seeded From UniProt

complete

enables

GO:0003824

catalytic activity

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0081

F

Seeded From UniProt

complete

involved_in

GO:0008152

metabolic process

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0326

P

Seeded From UniProt

complete

involved_in

GO:0019835

cytolysis

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0081

P

Seeded From UniProt

complete

enables

GO:0016798

hydrolase activity, acting on glycosyl bonds

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0326

F

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Kurushima, J et al. (2013) Bacteriocin protein BacL1 of Enterococcus faecalis is a peptidoglycan D-isoglutamyl-L-lysine endopeptidase. J. Biol. Chem. 288 36915-25 PubMed GONUTS page