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ENTFC:VANR

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Species (Taxon ID) Enterococcus faecium (Streptococcus faecium). (1352)
Gene Name(s) vanR
Protein Name(s) Regulatory protein VanR
External Links
UniProt Q06239
EMBL M97297
M68910
M84146
PIR A41838
RefSeq WP_001280781.1
YP_001019038.1
YP_001974799.1
YP_002128396.1
YP_004172619.1
YP_006937552.1
YP_009086370.1
YP_009090099.1
YP_976080.1
ProteinModelPortal Q06239
GeneID 10164673
13874699
4670248
4783154
6385885
6779665
KEGG pg:10164673
pg:13874699
pg:4670248
pg:4783154
pg:6385885
pg:6779665
KO K18349
GO GO:0005737
GO:0003677
GO:0071555
GO:0000160
GO:0006355
GO:0046677
GO:0006351
Gene3D 1.10.10.10
InterPro IPR011006
IPR001867
IPR016032
IPR001789
IPR011991
Pfam PF00072
PF00486
SMART SM00448
SM00862
SUPFAM SSF46894
SSF52172
PROSITE PS51755
PS50110

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0043433

negative regulation of sequence-specific DNA binding transcription factor activity

PMID:8981985[1]

ECO:0000316

UniProtKB:Q06240


P

Figure 4 shows that VanR by itself expresses the operon constitutively, and the authors conclude that VanS works by inhibiting VanR in the absence of inducer

complete
CACAO 11268

involved_in

GO:0000160

phosphorelay signal transduction system

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001789
InterPro:IPR001867

P

Seeded From UniProt

complete

enables

GO:0003677

DNA binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001867
InterPro:IPR016032

F

Seeded From UniProt

complete

involved_in

GO:0006355

regulation of transcription, DNA-templated

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001867
InterPro:IPR016032

P

Seeded From UniProt

complete

involved_in

GO:0071555

cell wall organization

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0961

P

Seeded From UniProt

complete

involved_in

GO:0000160

phosphorelay signal transduction system

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0902

P

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0963
UniProtKB-SubCell:SL-0086

C

Seeded From UniProt

complete

involved_in

GO:0046677

response to antibiotic

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0046

P

Seeded From UniProt

complete

enables

GO:0003677

DNA binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0238

F

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Arthur, M et al. (1997) The VanS sensor negatively controls VanR-mediated transcriptional activation of glycopeptide resistance genes of Tn1546 and related elements in the absence of induction. J. Bacteriol. 179 97-106 PubMed GONUTS page