ENTFC:Q9EZQ9

Species (Taxon ID)	Enterococcus faecium (Streptococcus faecium). (1352)
Gene Name(s)	vanD4 (ECO:0000313 with EMBL:AAG37026.1)
Protein Name(s)	D-alanine--D-alanine ligase (ECO:0000256 with HAMAP-Rule:MF_00047) D-Ala-D-Ala ligase (ECO:0000256 with HAMAP-Rule:MF_00047) D-alanylalanine synthetase (ECO:0000256 with HAMAP-Rule:MF_00047)
External Links
UniProt	Q9EZQ9
EMBL	AF277571 AY082011
ProteinModelPortal	Q9EZQ9
SMR	Q9EZQ9
GO	GO:0005737 GO:0005524 GO:0008716 GO:0000287 GO:0030145 GO:0071555 GO:0009252 GO:0008360
Gene3D	3.30.1490.20 3.30.470.20 3.40.50.20
HAMAP	MF_00047
InterPro	IPR011761 IPR013815 IPR013816 IPR000291 IPR005905 IPR011095 IPR011127 IPR016185
PANTHER	PTHR23132
Pfam	PF07478 PF01820
SUPFAM	SSF52440
TIGRFAMs	TIGR01205
PROSITE	PS50975 PS00843 PS00844

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
	GO:0046677	response to antibiotic	PMID:15388450	ECO:0000314			P		Table 2 shows that enterococci with VanD have high minimum inhibitory concentrations (MIC) of vancomycin.	complete CACAO 4913
	GO:0016805	dipeptidase activity	PMID:15388450	ECO:0000314			F		Table 6 shows the dipeptidase activity of enterococci with VanD.	complete CACAO 4914
enables	GO:0005524	ATP binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR011761 InterPro:IPR013815	F		Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR005905	C		Seeded From UniProt	complete
enables	GO:0008716	D-alanine-D-alanine ligase activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR005905 InterPro:IPR011095	F		Seeded From UniProt	complete
enables	GO:0046872	metal ion binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR011761	F		Seeded From UniProt	complete
enables	GO:0008716	D-alanine-D-alanine ligase activity	GO_REF:0000003	ECO:0000501	evidence used in automatic assertion	EC:6.3.2.4	F		Seeded From UniProt	complete
enables	GO:0005524	ATP binding	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-0067	F		Seeded From UniProt	complete
involved_in	GO:0009252	peptidoglycan biosynthetic process	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-0573	P		Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-0963	C		Seeded From UniProt	complete
enables	GO:0016874	ligase activity	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-0436	F		Seeded From UniProt	complete
enables	GO:0000166	nucleotide binding	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-0547	F		Seeded From UniProt	complete
involved_in	GO:0008360	regulation of cell shape	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-0133	P		Seeded From UniProt	complete
enables	GO:0046872	metal ion binding	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-0479	F		Seeded From UniProt	complete
involved_in	GO:0071555	cell wall organization	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-0961	P		Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000040	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-SubCell:SL-0086	C		Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000104	ECO:0000256	match to sequence model evidence used in automatic assertion	UniRule:UR000001246	C		Seeded From UniProt	complete
involved_in	GO:0009252	peptidoglycan biosynthetic process	GO_REF:0000104	ECO:0000256	match to sequence model evidence used in automatic assertion	UniRule:UR000001246	P		Seeded From UniProt	complete
enables	GO:0005524	ATP binding	GO_REF:0000104	ECO:0000256	match to sequence model evidence used in automatic assertion	UniRule:UR000414645	F		Seeded From UniProt	complete
enables	GO:0008716	D-alanine-D-alanine ligase activity	GO_REF:0000104	ECO:0000256	match to sequence model evidence used in automatic assertion	UniRule:UR000001246	F		Seeded From UniProt	complete
enables	GO:0000166	nucleotide binding	GO_REF:0000104	ECO:0000256	match to sequence model evidence used in automatic assertion	UniRule:UR000414645	F		Seeded From UniProt	complete
involved_in	GO:0009252	peptidoglycan biosynthetic process	GO_REF:0000041	ECO:0000322	imported manually asserted information used in automatic assertion	UniPathway:UPA00219	P		Seeded From UniProt	complete
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References

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