ENTFC:I6ZX04

Species (Taxon ID)	Enterococcus faecium (Streptococcus faecium). (1352)
Gene Name(s)	asrR (ECO:0000313 with EMBL:AFO10113.1)
Protein Name(s)	MarR family transcriptional regulator (ECO:0000313 with EMBL:AFO10113.1)
External Links
UniProt	I6ZX04
EMBL	JQ390466
STRING	565664.EFXG_01461
eggNOG	ENOG4105K56 ENOG4111TPH
GO	GO:0003677 GO:0003700 GO:0006351
Gene3D	1.10.10.10
InterPro	IPR000835 IPR011991
Pfam	PF01047
PRINTS	PR00598
SMART	SM00347
SUPFAM	SSF46785
PROSITE	PS50995

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Notes	Status
	GO:1900232	negative regulation of single-species biofilm formation on inanimate substrate	PMID:22876178^[1]	ECO:0000315			P	Figure 7B indicates that a biofilm is formed on polystyrene with an asrR knockout mutant, whereas the parental strain produces no biofilm. As a result, asrR negatively regulates biofilm formation on an inanimate substrate.	complete CACAO 11725
	GO:0034115	negative regulation of heterotypic cell-cell adhesion	PMID:22876178^[1]	ECO:0000315			P	Figure 7C indicates that asrR knockout mutants are more adherent to HT-29 cells than cells from the parental strain. As a result, asrR negatively regulates heterotypic cell-cell adhesion.	complete CACAO 11743
enables	GO:0003700	DNA-binding transcription factor activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000835	F	Seeded From UniProt	complete
involved_in	GO:0006355	regulation of transcription, DNA-templated	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000835	P	Seeded From UniProt	complete
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↑ ^1.0 ^1.1 Lebreton, F et al. (2012) AsrR is an oxidative stress sensing regulator modulating Enterococcus faecium opportunistic traits, antimicrobial resistance, and pathogenicity. PLoS Pathog. 8 e1002834 PubMed GONUTS page