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ENTFC:C7EME7

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Species (Taxon ID) Enterococcus faecium (Streptococcus faecium). (1352)
Gene Name(s) vanX (ECO:0000313 with EMBL:ACU27886.1)
Protein Name(s) D,D-dipeptidase (ECO:0000313 with EMBL:ACU27886.1)
External Links
UniProt C7EME7
EMBL GQ273977
GO GO:0005618
GO:0016805
GO:0008237
Gene3D 3.30.1380.10
HAMAP MF_01924
InterPro IPR000755
IPR009045
Pfam PF01427
PIRSF PIRSF026671
SUPFAM SSF55166

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

Contributes to

GO:0010628

positive regulation of gene expression

PMID:8981985[1]

ECO:0000314

P

Figure 3 shows bar graphs that contain data obtained from enzyme assays that measured the specific activity of the vanX gene at various levels of Vancomycin concentration. These graphs show that as the concentration of Vancomycin increases, the activity of vanX also increases. Since the concentration of the antibiotic effects the activity of the gene, it shows that the expression of vanX is increased as the concentration of Vancomycin increases.

complete
CACAO 11293

involved_in

GO:0006508

proteolysis

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000755

P

Seeded From UniProt

complete

enables

GO:0008237

metallopeptidase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000755

F

Seeded From UniProt

complete

enables

GO:0016805

dipeptidase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000755

F

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Arthur, M et al. (1997) The VanS sensor negatively controls VanR-mediated transcriptional activation of glycopeptide resistance genes of Tn1546 and related elements in the absence of induction. J. Bacteriol. 179 97-106 PubMed GONUTS page