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EHV2:VCLAP

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Species (Taxon ID) Equine herpesvirus 2 (strain 86/87) (EHV-2). (82831)
Gene Name(s) E10
Protein Name(s) CARD domain-containing protein E10
External Links
UniProt Q66677
EMBL U20824
PIR S55671
RefSeq NP_042674.1
ProteinModelPortal Q66677
GeneID 1461015
Proteomes UP000007083
GO GO:0020002
GO:0016020
GO:0039652
GO:0042981
Gene3D 1.10.533.10
InterPro IPR001315
IPR011029
Pfam PF00619
SUPFAM SSF47986
PROSITE PS50209

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

part_of

GO:0020002

host cell plasma membrane

PMID:11238466[1]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:1903076

regulation of protein localization to plasma membrane

PMID:11238466[1]

ECO:0000314

direct assay evidence used in manual assertion

P

has_regulation_target:(UniProtKB:O95999)

Seeded From UniProt

complete

involved_in

GO:0051092

positive regulation of NF-kappaB transcription factor activity

PMID:11238466[1]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0043621

protein self-association

PMID:10187771[2]

ECO:0000353

physical interaction evidence used in manual assertion

UniProtKB:Q66677

F

Seeded From UniProt

complete

involved_in

GO:0075131

positive regulation by symbiont of host protein kinase-mediated signal transduction

PMID:10187771[2]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0085033

positive regulation by symbiont of host I-kappaB kinase/NF-kappaB cascade

PMID:10187771[2]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0042981

regulation of apoptotic process

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001315

P

Seeded From UniProt

complete

involved_in

GO:0051092

positive regulation of NF-kappaB transcription factor activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR033238

P

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0472

C

Seeded From UniProt

complete

part_of

GO:0020002

host cell plasma membrane

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-1032
UniProtKB-SubCell:SL-0375

C

Seeded From UniProt

complete

part_of

GO:0033644

host cell membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-1043

C

Seeded From UniProt

complete

involved_in

GO:0016032

viral process

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0945

P

Seeded From UniProt

complete

involved_in

GO:0039652

activation by virus of host NF-kappaB transcription factor activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-1074

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 Thome, M et al. (2001) Equine herpesvirus protein E10 induces membrane recruitment and phosphorylation of its cellular homologue, bcl-10. J. Cell Biol. 152 1115-22 PubMed GONUTS page
  2. 2.0 2.1 2.2 Thome, M et al. (1999) Equine herpesvirus-2 E10 gene product, but not its cellular homologue, activates NF-kappaB transcription factor and c-Jun N-terminal kinase. J. Biol. Chem. 274 9962-8 PubMed GONUTS page