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ECOLX:Q2EUT0

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Species (Taxon ID) Escherichia coli. (562)
Gene Name(s) accD (ECO:0000313 with EMBL:ABD19992.1)
Protein Name(s) AccD (ECO:0000313 with EMBL:ABD19992.1)
External Links
UniProt Q2EUT0
EMBL DQ362291
DQ362292
DQ362293
GO GO:0009317
GO:0003989
GO:0006633
Gene3D 3.90.226.10
HAMAP MF_01395
InterPro IPR000438
IPR000022
IPR029045
IPR011762
Pfam PF01039
PRINTS PR01070
SUPFAM SSF52096
TIGRFAMs TIGR00515
PROSITE PS50980

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0003989

acetyl-CoA carboxylase activity

PMID:19965770[1]

ECO:0000315

F

The effect of the cysteine mutations on enzymatic activity was assessed using a coupled enzyme assay. The kinetic results indicate that mutation of individual cysteine residues 27, 46 and 49 decreases the Vmax only 8- to 11-fold, whereas the Vmax for the C30A variant decreases by over 100-fold. Table 2

complete
CACAO 4794

enables

GO:0003989

acetyl-CoA carboxylase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000438

F

Seeded From UniProt

complete

involved_in

GO:0006633

fatty acid biosynthetic process

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000438

P

Seeded From UniProt

complete

part_of

GO:0009317

acetyl-CoA carboxylase complex

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000438

C

Seeded From UniProt

complete

enables

GO:0016740

transferase activity

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0808

F

Seeded From UniProt

complete

enables

GO:0000166

nucleotide binding

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0547

F

Seeded From UniProt

complete

enables

GO:0046872

metal ion binding

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0479

F

Seeded From UniProt

complete

involved_in

GO:0006629

lipid metabolic process

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0443

P

Seeded From UniProt

complete

involved_in

GO:0006631

fatty acid metabolic process

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0276

P

Seeded From UniProt

complete

involved_in

GO:0006633

fatty acid biosynthetic process

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0275

P

Seeded From UniProt

complete

enables

GO:0005524

ATP binding

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0067

F

Seeded From UniProt

complete

involved_in

GO:2001295

malonyl-CoA biosynthetic process

GO_REF:0000041

ECO:0000322

imported manually asserted information used in automatic assertion

UniPathway:UPA00655

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Meades, G Jr et al. (2010) A tale of two functions: enzymatic activity and translational repression by carboxyltransferase. Nucleic Acids Res. 38 1217-27 PubMed GONUTS page