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ECOLX:F8UCG3

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Species (Taxon ID) Escherichia coli. (562)
Gene Name(s) crp (ECO:0000313 with EMBL:AEH68826.1)
Protein Name(s) Crp (ECO:0000313 with EMBL:AEH68826.1)
External Links
UniProt F8UCG3
EMBL JF781281
GO GO:0005622
GO:0003677
GO:0003700
GO:0006351
Gene3D 1.10.10.10
2.60.120.10
InterPro IPR018490
IPR018488
IPR000595
IPR012318
IPR014710
IPR001808
IPR018335
IPR011991
Pfam PF00027
PF00325
PRINTS PR00034
SMART SM00100
SM00419
SUPFAM SSF51206
PROSITE PS00888
PS00889
PS50042
PS00042
PS51063

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0003677

DNA binding

PMID:7551052[1]

ECO:0000314

F

Figures 3-6 in reference show gel mobility retardation when Crp mixed with DNA from promoter region.

complete

GO:0003700

sequence-specific DNA binding transcription factor activity

PMID:7551052[1]

ECO:0000314

F

Figures 3-6 show that when select portions of the promoter suspected to be Crp binding sites were removed/absent, the gel retardation forms associated with those complexes disappeared.

complete

GO:0006355

regulation of transcription, DNA-dependent

PMID:4350344[2]

ECO:0000315

P

Table 2 shows lac+ mutants derived in Crp- cells that arose from changes to the promoter of lacZ-Y-A. The mutations were not in the lac operator regions.

complete

enables

GO:0003677

DNA binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR012318

F

Seeded From UniProt

complete

enables

GO:0003700

DNA-binding transcription factor activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR018335

F

Seeded From UniProt

complete

involved_in

GO:0006355

regulation of transcription, DNA-templated

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR012318
InterPro:IPR018335

P

Seeded From UniProt

complete

enables

GO:0003677

DNA binding

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0238

F

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Ramseier, TM & Saier, MH Jr (1995) cAMP-cAMP receptor protein complex: five binding sites in the control region of the Escherichia coli mannitol operon. Microbiology (Reading, Engl.) 141 ( Pt 8) 1901-7 PubMed GONUTS page
  2. Arditti, R et al. (1973) Cyclic adenosine monophosphate-independent mutants of the lactose operon of Escherichia coli. J. Bacteriol. 114 652-5 PubMed GONUTS page