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ECOLX:E2QMH3

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Species (Taxon ID) Escherichia coli. (562)
Gene Name(s) No Information Provided.
Protein Name(s) DNA replication terminus site-binding protein (ECO:0000256 with HAMAP-Rule:MF_00483)

Ter-binding protein (ECO:0000256 with HAMAP-Rule:MF_00483)

External Links
UniProt E2QMH3
EMBL CU651637
RefSeq YP_002556502.1
EnsemblBacteria CAP76109
GeneID 7394226
KEGG elf:LF82_2336
PATRIC 48653090
KO K10748
Proteomes UP000010085
GO GO:0005737
GO:0003677
GO:0006274
GO:0006607
Gene3D 3.50.14.10
HAMAP MF_00483
InterPro IPR008865
Pfam PF05472
SUPFAM SSF56596
TIGRFAMs TIGR02648

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0006607

NLS-bearing substrate import into nucleus

PMID:20126275[1]

IMP: Inferred from Mutant Phenotype

P

A series of N- and C- terminal deletion mutants of Tus were constructed which were fused to GFP to determine the subcellular distribution of green fluorescence in the transduced cells. Figure 2A shows that the fusion of amino acids 218 to 309 of Tus to the C-terminus of GFP restored nuclear targeting, defining the NLS sequence of Tus. Further depicted in Figure 3A, alteration of any one of the basic amino acids 218-309 resulted in pronounced perturbation of nuclear targeting of the fusion proteins.

complete
CACAO 3985

GO:0003677

DNA binding

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR008865

F

Seeded From UniProt

complete

GO:0003677

DNA binding

GO_REF:0000020

IEA: Inferred from Electronic Annotation

HAMAP:MF_00483

F

Seeded From UniProt

complete

GO:0003677

DNA binding

GO_REF:0000038

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0238

F

Seeded From UniProt

complete

GO:0005737

cytoplasm

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR008865

C

Seeded From UniProt

complete

GO:0005737

cytoplasm

GO_REF:0000020

IEA: Inferred from Electronic Annotation

HAMAP:MF_00483

C

Seeded From UniProt

complete

GO:0005737

cytoplasm

GO_REF:0000038

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0963

C

Seeded From UniProt

complete

GO:0005737

cytoplasm

GO_REF:0000040

IEA: Inferred from Electronic Annotation

UniProtKB-SubCell:SL-0086

C

Seeded From UniProt

complete

GO:0006260

DNA replication

GO_REF:0000038

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0235

P

Seeded From UniProt

complete

GO:0006274

DNA replication termination

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR008865

P

Seeded From UniProt

complete

GO:0006274

DNA replication termination

GO_REF:0000020

IEA: Inferred from Electronic Annotation

HAMAP:MF_00483

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Kaczmarczyk, SJ et al. (2010) Tus, an E. coli protein, contains mammalian nuclear targeting and exporting signals. PLoS ONE 5 e8889 PubMed GONUTS page