ECOLX:A0A023Z1P7

Species (Taxon ID)	Escherichia coli O145:H28 str. RM12581. (1248823)
Gene Name(s)	mltA (ECO:0000313 with EMBL:AHY72152.1)
Protein Name(s)	Membrane-bound lytic murein transglycosylase A (ECO:0000313 with EMBL:AHY72152.1)
External Links
UniProt	A0A023Z1P7
EMBL	CP007136
RefSeq	WP_000678646.1
ProteinModelPortal	A0A023Z1P7
EnsemblBacteria	AHY72152
OMA	KREDMSM
Proteomes	UP000025231
GO	GO:0019867 GO:0004553 GO:0009254
Gene3D	2.40.40.10
InterPro	IPR010611 IPR005300 IPR009009
Pfam	PF06725 PF03562
SMART	SM00925
SUPFAM	SSF50685

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
	GO:2000966	regulation of cell wall polysaccharide catabolic process	PMID:16615077	ECO:0000250		UniProtKB:A0A0G4BQJ3	P		MltA is a lytic transglycosylase of Gram-negative bacteria that cleaves the beta-1,4 glycosidic linkages between N-acetylmuramic acid (MurNAc) and N-acetylglucosamine (GlcNAc) in peptidoglycan. We have determined the crystal structures of MltA from Neisseria gonorrhoeae and Escherichia coli (NgMltA and EcMltA), which have only 21.5% sequence identity but have 2 main domains separated by a deep grove pointing that they are both MltA proteins.	complete CACAO 11434
enables	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR005300 InterPro:IPR010611	F		Seeded From UniProt	complete
involved_in	GO:0009254	peptidoglycan turnover	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR010611	P		Seeded From UniProt	complete
part_of	GO:0019867	outer membrane	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR010611	C		Seeded From UniProt	complete
enables	GO:0016829	lyase activity	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-0456	F		Seeded From UniProt	complete
involved_in	GO:0071555	cell wall organization	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-0961	P		Seeded From UniProt	complete
involved_in	GO:0009254	peptidoglycan turnover	GO_REF:0000104	ECO:0000256	match to sequence model evidence used in automatic assertion	UniRule:UR000129104	P		Seeded From UniProt	complete
enables	GO:0016829	lyase activity	GO_REF:0000104	ECO:0000256	match to sequence model evidence used in automatic assertion	UniRule:UR000129104	F		Seeded From UniProt	complete
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References

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