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ECOLI:ZUPT

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Species (Taxon ID) Escherichia coli (strain K12). (83333)
Gene Name(s) zupT (synonyms: ygiE)
Protein Name(s) Zinc transporter ZupT
External Links
UniProt P0A8H3
EMBL M77129
U28377
U00096
AP009048
PIR S22363
RefSeq NP_417512.1
YP_491232.1
ProteinModelPortal P0A8H3
STRING 511145.b3040
TCDB 2.A.5.5.1
EnsemblBacteria AAC76076
BAE77096
GeneID 12930256
947035
KEGG ecj:Y75_p2966
eco:b3040
PATRIC 32121490
EchoBASE EB1155
EcoGene EG11167
eggNOG COG0428
HOGENOM HOG000232704
InParanoid P0A8H3
KO K07238
OMA NMDIAGS
OrthoDB EOG6M3PH0
PhylomeDB P0A8H3
BioCyc EcoCyc:EG11167-MONOMER
ECOL316407:JW3008-MONOMER
MetaCyc:EG11167-MONOMER
PRO PR:P0A8H3
Proteomes UP000000318
UP000000625
Genevestigator P0A8H3
GO GO:0016021
GO:0005886
GO:0015086
GO:0015087
GO:0015088
GO:0015093
GO:0005384
GO:0070574
GO:0006824
GO:0035434
GO:0015684
GO:0071421
GO:0006829
HAMAP MF_00548
InterPro IPR003689
IPR023498
Pfam PF02535

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0006829

zinc ion transport

PMID:11790762[1]

ECO:0000315

P

Fig. 3: Induced expression of zupT in mutants lacking all zinc transporters yielded much greater uptake of zinc than the controls lacking transduction by the zupT vector.

complete
CACAO 4312

involved_in

GO:0006829

zinc ion transport

PMID:11790762[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0071577

zinc ion transmembrane transport

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000115815
TAIR:locus:2087705
TAIR:locus:2123787
TAIR:locus:2174098
UniProtKB:Q4WHX5
UniProtKB:Q4WKR5
UniProtKB:Q4WPK3
UniProtKB:Q9NY26

P

Seeded From UniProt

complete

enables

GO:0005385

zinc ion transmembrane transporter activity

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0033096
FB:FBgn0033097
MGI:MGI:1353474
MGI:MGI:1917056
MGI:MGI:2147269
MGI:MGI:2684326
PANTHER:PTN000115815
SGD:S000001658
TAIR:locus:2062576
TAIR:locus:2087705
TAIR:locus:2206011
UniProtKB:Q4WHX5
UniProtKB:Q9NP94

F

Seeded From UniProt

complete

involved_in

GO:0070574

cadmium ion transmembrane transport

PMID:20225068[3]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0015093

ferrous iron transmembrane transporter activity

PMID:15716430[4]

ECO:0000316

genetic interaction evidence used in manual assertion

EcoliWiki:entC
EcoliWiki:fecA
EcoliWiki:fecB
EcoliWiki:fecC
EcoliWiki:fecD
EcoliWiki:fecE
EcoliWiki:feoA
EcoliWiki:feoB
EcoliWiki:feoC
EcoliWiki:mntH

F

Seeded From UniProt

complete

enables

GO:0015087

cobalt ion transmembrane transporter activity

PMID:15716430[4]

ECO:0000316

genetic interaction evidence used in manual assertion

EcoliWiki:corA

F

Seeded From UniProt

complete

enables

GO:0015086

cadmium ion transmembrane transporter activity

PMID:20225068[3]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

PMID:15716430[4]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

enables

GO:0005384

manganese ion transmembrane transporter activity

PMID:15716430[4]

ECO:0000315

mutant phenotype evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0005375

copper ion transmembrane transporter activity

PMID:11790762[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0006824

cobalt ion transport

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0015087

P

Seeded From UniProt

complete

involved_in

GO:0034755

iron ion transmembrane transport

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0015093

P

Seeded From UniProt

complete

involved_in

GO:0035434

copper ion transmembrane transport

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0005375

P

Seeded From UniProt

complete

involved_in

GO:0071421

manganese ion transmembrane transport

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0005384

P

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR003689

C

Seeded From UniProt

complete

involved_in

GO:0030001

metal ion transport

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR003689

P

Seeded From UniProt

complete

enables

GO:0046873

metal ion transmembrane transporter activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR003689

F

Seeded From UniProt

complete

involved_in

GO:0055085

transmembrane transport

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR003689

P

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000064680

C

Seeded From UniProt

complete

involved_in

GO:0006829

zinc ion transport

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000064680

P

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0472

C

Seeded From UniProt

complete

part_of

GO:0016021

integral component of membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0812

C

Seeded From UniProt

complete

involved_in

GO:0006811

ion transport

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0406

P

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-1003
UniProtKB-SubCell:SL-0039

C

Seeded From UniProt

complete

involved_in

GO:0006829

zinc ion transport

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0864

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 Grass, G et al. (2002) ZupT is a Zn(II) uptake system in Escherichia coli. J. Bacteriol. 184 864-6 PubMed GONUTS page
  2. 2.0 2.1 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
  3. 3.0 3.1 Taudte, N & Grass, G (2010) Point mutations change specificity and kinetics of metal uptake by ZupT from Escherichia coli. Biometals 23 643-56 PubMed GONUTS page
  4. 4.0 4.1 4.2 4.3 Grass, G et al. (2005) The metal permease ZupT from Escherichia coli is a transporter with a broad substrate spectrum. J. Bacteriol. 187 1604-11 PubMed GONUTS page