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ECOLI:TSX

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Species (Taxon ID) Escherichia coli (strain K12). (83333)
Gene Name(s) tsx (synonyms: nupA)
Protein Name(s) Nucleoside-specific channel-forming protein tsx
External Links
UniProt P0A927
EMBL M57685
U82664
U00096
AP009048
PIR JQ0798
RefSeq NP_414945.1
YP_488703.1
PDB 1TLW
1TLY
1TLZ
PDBsum 1TLW
1TLY
1TLZ
ProteinModelPortal P0A927
SMR P0A927
STRING 511145.b0411
TCDB 1.B.10.1.1
PaxDb P0A927
PRIDE P0A927
EnsemblBacteria AAC73514
BAE76191
GeneID 12934188
946242
KEGG ecj:Y75_p0399
eco:b0411
PATRIC 32115971
EchoBASE EB1028
EcoGene EG11035
eggNOG COG3248
HOGENOM HOG000273630
KO K05517
OMA GTDIDTH
OrthoDB EOG6B35ZS
BioCyc EcoCyc:EG11035-MONOMER
ECOL316407:JW0401-MONOMER
MetaCyc:EG11035-MONOMER
EvolutionaryTrace P0A927
PRO PR:P0A927
Proteomes UP000000318
UP000000625
Genevestigator P0A927
GO GO:0009279
GO:0046930
GO:0015471
GO:0006811
GO:1901642
GO:0015858
GO:0046718
Gene3D 2.40.230.20
InterPro IPR003055
IPR018013
Pfam PF03502
PRINTS PR01277
SUPFAM SSF111364

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0009279

cell outer membrane

PMID:10806384[1]

ECO:0000314

C

Table 1

complete

part_of

GO:0046930

pore complex

PMID:15272310[2]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0046718

viral entry into host cell

PMID:791677[3]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0015858

nucleoside transport

PMID:2458926[4]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0015471

nucleoside-specific channel forming porin activity

PMID:2458926[4]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

part_of

GO:0009279

cell outer membrane

PMID:2458926[4]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0055085

transmembrane transport

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0015288

P

Seeded From UniProt

complete

involved_in

GO:1901642

nucleoside transmembrane transport

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0005337

P

Seeded From UniProt

complete

involved_in

GO:1901642

nucleoside transmembrane transport

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0015471

P

Seeded From UniProt

complete

enables

GO:0005337

nucleoside transmembrane transporter activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR003055

F

Seeded From UniProt

complete

part_of

GO:0009279

cell outer membrane

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR003055
InterPro:IPR018013
InterPro:IPR036777

C

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0472

C

Seeded From UniProt

complete

enables

GO:0015288

porin activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0626

F

Seeded From UniProt

complete

part_of

GO:0016021

integral component of membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0812

C

Seeded From UniProt

complete

part_of

GO:0046930

pore complex

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0626

C

Seeded From UniProt

complete

part_of

GO:0009279

cell outer membrane

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0998
UniProtKB-SubCell:SL-0040

C

Seeded From UniProt

complete

involved_in

GO:0006811

ion transport

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0406

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Molloy, MP et al. (2000) Proteomic analysis of the Escherichia coli outer membrane. Eur. J. Biochem. 267 2871-81 PubMed GONUTS page
  2. Ye, J & van den Berg, B (2004) Crystal structure of the bacterial nucleoside transporter Tsx. EMBO J. 23 3187-95 PubMed GONUTS page
  3. Hantke, K (1976) Phage T6--colicin K receptor and nucleoside transport in Escherichia coli. FEBS Lett. 70 109-12 PubMed GONUTS page
  4. 4.0 4.1 4.2 Benz, R et al. (1988) Characterization of the nucleoside-binding site inside the Tsx channel of Escherichia coli outer membrane. Reconstitution experiments with lipid bilayer membranes. Eur. J. Biochem. 176 699-705 PubMed GONUTS page