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ECOLI:TRUB
Contents
| Species (Taxon ID) | Escherichia coli (strain K12). (83333) | |
| Gene Name(s) | truB (synonyms: yhbA) | |
| Protein Name(s) | tRNA pseudouridine synthase B
Protein p35 tRNA pseudouridine(55) synthase Psi55 synthase tRNA pseudouridylate synthase tRNA-uridine isomerase | |
| External Links | ||
| UniProt | P60340 | |
| EMBL | X13270 X13775 U18997 U00096 AP009048 S79856 | |
| PIR | S01916 | |
| RefSeq | NP_417635.1 YP_491353.1 | |
| PDB | 1K8W 1R3F 1ZL3 | |
| PDBsum | 1K8W 1R3F 1ZL3 | |
| ProteinModelPortal | P60340 | |
| SMR | P60340 | |
| IntAct | P60340 | |
| STRING | 511145.b3166 | |
| PaxDb | P60340 | |
| PRIDE | P60340 | |
| EnsemblBacteria | AAC76200 BAE77212 | |
| GeneID | 12933440 947687 | |
| KEGG | ecj:Y75_p3088 eco:b3166 | |
| PATRIC | 32121750 | |
| EchoBASE | EB1164 | |
| EcoGene | EG11177 | |
| eggNOG | COG0130 | |
| HOGENOM | HOG000231223 | |
| InParanoid | P60340 | |
| KO | K03177 | |
| OMA | YELQFIR | |
| OrthoDB | EOG6358D3 | |
| PhylomeDB | P60340 | |
| BioCyc | EcoCyc:EG11177-MONOMER ECOL316407:JW3135-MONOMER MetaCyc:EG11177-MONOMER | |
| EvolutionaryTrace | P60340 | |
| PRO | PR:P60340 | |
| Proteomes | UP000000318 UP000000625 | |
| Genevestigator | P60340 | |
| GO | GO:0009982 GO:0003723 GO:0001522 GO:0031119 | |
| Gene3D | 2.30.130.10 | |
| HAMAP | MF_01080 | |
| InterPro | IPR002501 IPR020103 IPR015947 IPR014780 IPR015240 | |
| PANTHER | PTHR13767 | |
| Pfam | PF09157 PF01509 | |
| SUPFAM | SSF55120 SSF88697 | |
| TIGRFAMs | TIGR00431 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
|
involved_in |
GO:1990481 |
mRNA pseudouridine synthesis |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000349172 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0009982 |
pseudouridine synthase activity |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
EcoGene:EG11177 |
F |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0006400 |
tRNA modification |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000349172 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005739 |
mitochondrion |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000349172 |
C |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0034337 |
RNA folding |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0031119 |
tRNA pseudouridine synthesis |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0009982 |
pseudouridine synthase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005829 |
cytosol |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0001522 |
pseudouridine synthesis |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0000049 |
tRNA binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0001522 |
pseudouridine synthesis |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003723 |
RNA binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
InterPro:IPR014780 |
F |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0006396 |
RNA processing |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0009451 |
RNA modification |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0009982 |
pseudouridine synthase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0106029 |
tRNA pseudouridine synthase activity |
ECO:0000501 |
evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0009982 |
pseudouridine synthase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000100585 |
F |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0031119 |
tRNA pseudouridine synthesis |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000100585 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0008033 |
tRNA processing |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016853 |
isomerase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
- ↑ 2.0 2.1 Keffer-Wilkes, LC et al. (2016) RNA modification enzyme TruB is a tRNA chaperone. Proc. Natl. Acad. Sci. U.S.A. 113 14306-14311 PubMed GONUTS page
- ↑ 3.0 3.1 Gutgsell, N et al. (2000) Deletion of the Escherichia coli pseudouridine synthase gene truB blocks formation of pseudouridine 55 in tRNA in vivo, does not affect exponential growth, but confers a strong selective disadvantage in competition with wild-type cells. RNA 6 1870-81 PubMed GONUTS page
- ↑ Nurse, K et al. (1995) Purification, cloning, and properties of the tRNA psi 55 synthase from Escherichia coli. RNA 1 102-12 PubMed GONUTS page
- ↑ Ishihama, Y et al. (2008) Protein abundance profiling of the Escherichia coli cytosol. BMC Genomics 9 102 PubMed GONUTS page
