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ECOLI:TPX
Contents
| Species (Taxon ID) | Escherichia coli (strain K12). (83333) | |
| Gene Name(s) | tpx (synonyms: yzzJ) | |
| Protein Name(s) | Thiol peroxidase
Scavengase P20 | |
| External Links | ||
| UniProt | P0A862 | |
| EMBL | U33213 U93212 U00096 AP009048 | |
| PIR | JC5504 | |
| RefSeq | NP_415840.1 YP_489593.1 | |
| PDB | 1QXH 3HVS 3HVV 3HVX 3I43 4AF2 | |
| PDBsum | 1QXH 3HVS 3HVV 3HVX 3I43 4AF2 | |
| ProteinModelPortal | P0A862 | |
| SMR | P0A862 | |
| BioGrid | 850247 | |
| DIP | DIP-31857N | |
| IntAct | P0A862 | |
| STRING | 511145.b1324 | |
| PeroxiBase | 6007 | |
| PhosSite | P0810441 | |
| SWISS-2DPAGE | P0A862 | |
| PaxDb | P0A862 | |
| PRIDE | P0A862 | |
| EnsemblBacteria | AAC74406 BAA14906 | |
| GeneID | 12931157 945880 | |
| KEGG | ecj:Y75_p1300 eco:b1324 | |
| PATRIC | 32117922 | |
| EchoBASE | EB2538 | |
| EcoGene | EG12672 | |
| eggNOG | COG2077 | |
| HOGENOM | HOG000022345 | |
| InParanoid | P0A862 | |
| KO | K11065 | |
| OMA | ISCDLPF | |
| OrthoDB | EOG6NWBV8 | |
| PhylomeDB | P0A862 | |
| BioCyc | EcoCyc:G6660-MONOMER ECOL316407:JW1317-MONOMER MetaCyc:G6660-MONOMER | |
| EvolutionaryTrace | P0A862 | |
| PRO | PR:P0A862 | |
| Proteomes | UP000000318 UP000000625 | |
| Genevestigator | P0A862 | |
| GO | GO:0005737 GO:0042597 GO:0032843 GO:0008379 GO:0045454 GO:0034599 | |
| Gene3D | 3.40.30.10 | |
| HAMAP | MF_00269 | |
| InterPro | IPR002065 IPR013740 IPR012336 IPR018219 | |
| Pfam | PF08534 | |
| SUPFAM | SSF52833 | |
| PROSITE | PS51352 PS01265 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
|
involved_in |
GO:0034599 |
cellular response to oxidative stress |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0032843 |
hydroperoxide reductase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0008379 |
thioredoxin peroxidase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005829 |
cytosol |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005829 |
cytosol |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0098869 |
cellular oxidant detoxification |
ECO:0000366 |
evidence based on logical inference from automatic annotation used in automatic assertion |
GO:0016209 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0098869 |
cellular oxidant detoxification |
ECO:0000366 |
evidence based on logical inference from automatic annotation used in automatic assertion |
GO:0016209 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0098869 |
cellular oxidant detoxification |
ECO:0000364 |
evidence based on logical inference from manual annotation used in automatic assertion |
GO:0008379 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0098869 |
cellular oxidant detoxification |
ECO:0000366 |
evidence based on logical inference from automatic annotation used in automatic assertion |
GO:0016209 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0098869 |
cellular oxidant detoxification |
ECO:0000366 |
evidence based on logical inference from automatic annotation used in automatic assertion |
GO:0004601 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0098869 |
cellular oxidant detoxification |
ECO:0000366 |
evidence based on logical inference from automatic annotation used in automatic assertion |
GO:0051920 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0008379 |
thioredoxin peroxidase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016209 |
antioxidant activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016491 |
oxidoreductase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016684 |
oxidoreductase activity, acting on peroxide as acceptor |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0045454 |
cell redox homeostasis |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0055114 |
oxidation-reduction process |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0051920 |
peroxiredoxin activity |
ECO:0000501 |
evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016209 |
antioxidant activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000058574 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0008379 |
thioredoxin peroxidase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000058574 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0016491 |
oxidoreductase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004601 |
peroxidase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0042597 |
periplasmic space |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016209 |
antioxidant activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0055114 |
oxidation-reduction process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Cha, MK et al. (1996) Mutation and Mutagenesis of thiol peroxidase of Escherichia coli and a new type of thiol peroxidase family. J. Bacteriol. 178 5610-4 PubMed GONUTS page
- ↑ Baker, LM & Poole, LB (2003) Catalytic mechanism of thiol peroxidase from Escherichia coli. Sulfenic acid formation and overoxidation of essential CYS61. J. Biol. Chem. 278 9203-11 PubMed GONUTS page
- ↑ Cha, MK et al. (1995) Thioredoxin-linked "thiol peroxidase" from periplasmic space of Escherichia coli. J. Biol. Chem. 270 28635-41 PubMed GONUTS page
- ↑ Ishihama, Y et al. (2008) Protein abundance profiling of the Escherichia coli cytosol. BMC Genomics 9 102 PubMed GONUTS page
- ↑ Lopez-Campistrous, A et al. (2005) Localization, annotation, and comparison of the Escherichia coli K-12 proteome under two states of growth. Mol. Cell Proteomics 4 1205-9 PubMed GONUTS page
- ↑ Tao, K (2008) Subcellular localization and in vivo oxidation-reduction kinetics of thiol peroxidase in Escherichia coli. FEMS Microbiol. Lett. 289 41-5 PubMed GONUTS page
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