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ECOLI:TOP3
Contents
| Species (Taxon ID) | Escherichia coli (strain K12). (83333) | |
| Gene Name(s) | topB (ECO:0000255 with HAMAP-Rule:MF_00953) | |
| Protein Name(s) | DNA topoisomerase 3 (ECO:0000255 with HAMAP-Rule:MF_00953)
DNA topoisomerase III (ECO:0000255 with HAMAP-Rule:MF_00953) | |
| External Links | ||
| UniProt | P14294 | |
| EMBL | J05076 U00096 AP009048 | |
| PIR | JV0049 | |
| RefSeq | NP_416277.1 YP_490024.1 | |
| PDB | 1D6M 1I7D 2O19 2O54 2O59 2O5C 2O5E | |
| PDBsum | 1D6M 1I7D 2O19 2O54 2O59 2O5C 2O5E | |
| ProteinModelPortal | P14294 | |
| SMR | P14294 | |
| DIP | DIP-11012N | |
| IntAct | P14294 | |
| MINT | MINT-1224249 | |
| STRING | 511145.b1763 | |
| PaxDb | P14294 | |
| PRIDE | P14294 | |
| EnsemblBacteria | AAC74833 BAA15551 | |
| GeneID | 12930143 946141 | |
| KEGG | ecj:Y75_p1738 eco:b1763 | |
| PATRIC | 32118837 | |
| EchoBASE | EB1007 | |
| EcoGene | EG11014 | |
| eggNOG | COG0550 | |
| HOGENOM | HOG000086848 | |
| InParanoid | P14294 | |
| KO | K03169 | |
| OMA | GLIARQY | |
| OrthoDB | EOG60CWM6 | |
| PhylomeDB | P14294 | |
| BioCyc | EcoCyc:EG11014-MONOMER ECOL316407:JW1752-MONOMER MetaCyc:EG11014-MONOMER | |
| EvolutionaryTrace | P14294 | |
| PRO | PR:P14294 | |
| Proteomes | UP000000318 UP000000625 | |
| Genevestigator | P14294 | |
| GO | GO:0003677 GO:0003917 GO:0000287 GO:0051304 GO:0006310 GO:0006265 | |
| Gene3D | 1.10.460.10 2.70.20.10 3.40.50.140 | |
| HAMAP | MF_00953 | |
| InterPro | IPR000380 IPR003601 IPR023406 IPR013497 IPR013824 IPR013825 IPR023405 IPR003602 IPR005738 IPR006171 | |
| PANTHER | PTHR11390 | |
| Pfam | PF01131 PF01751 | |
| PRINTS | PR00417 | |
| SMART | SM00437 SM00436 SM00493 | |
| SUPFAM | SSF56712 | |
| TIGRFAMs | TIGR01056 | |
| PROSITE | PS00396 PS50880 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
|
involved_in |
GO:0051304 |
chromosome separation |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006310 |
DNA recombination |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003917 |
DNA topoisomerase type I activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003677 |
DNA binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
InterPro:IPR000380 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0003916 |
DNA topoisomerase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
InterPro:IPR003601 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0003917 |
DNA topoisomerase type I activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006265 |
DNA topological change |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
InterPro:IPR000380 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0003917 |
DNA topoisomerase type I activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000336027 |
F |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0006265 |
DNA topological change |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000336027 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0000287 |
magnesium ion binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000336027 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0003677 |
DNA binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0046872 |
metal ion binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016853 |
isomerase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003916 |
DNA topoisomerase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Nurse, P et al. (2003) Topoisomerase III can serve as the cellular decatenase in Escherichia coli. J. Biol. Chem. 278 8653-60 PubMed GONUTS page
- ↑ Lopez, CR et al. (2005) A role for topoisomerase III in a recombination pathway alternative to RuvABC. Mol. Microbiol. 58 80-101 PubMed GONUTS page
- ↑ Srivenugopal, KS et al. (1984) Escherichia coli DNA topoisomerase III: purification and characterization of a new type I enzyme. Biochemistry 23 1899-906 PubMed GONUTS page
