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ECOLI:THIH

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Species (Taxon ID) Escherichia coli (strain K12). (83333)
Gene Name(s) thiH
Protein Name(s) 2-iminoacetate synthase

Dehydroglycine synthase Tyrosine lyase

External Links
UniProt P30140
EMBL M88701
U00006
U00096
AP009048
PIR S35121
RefSeq NP_418417.1
YP_491471.1
ProteinModelPortal P30140
SMR P30140
DIP DIP-6869N
IntAct P30140
STRING 511145.b3990
PaxDb P30140
PRIDE P30140
EnsemblBacteria AAC76964
BAE77330
GeneID 12933915
948494
KEGG ecj:Y75_p3207
eco:b3990
PATRIC 32123501
EchoBASE EB1548
EcoGene EG11590
eggNOG COG1060
HOGENOM HOG000270732
InParanoid P30140
KO K03150
OMA LEQFEIS
OrthoDB EOG6RNQB0
PhylomeDB P30140
BioCyc EcoCyc:THIH-MONOMER
ECOL316407:JW3953-MONOMER
MetaCyc:THIH-MONOMER
UniPathway UPA00060
PRO PR:P30140
Proteomes UP000000318
UP000000625
Genevestigator P30140
GO GO:0036355
GO:0051539
GO:0005506
GO:0051536
GO:0016829
GO:0006974
GO:0009228
GO:0009229
Gene3D 3.20.20.70
InterPro IPR013785
IPR010722
IPR007197
IPR012726
Pfam PF06968
PF04055
SMART SM00876
TIGRFAMs TIGR02351

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

involved_in

GO:0006974

cellular response to DNA damage stimulus

PMID:11967071[1]

ECO:0000270

expression pattern evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0051539

4 iron, 4 sulfur cluster binding

PMID:17403671[2]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0036355

2-iminoacetate synthase activity

PMID:19923213[3]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0009228

thiamine biosynthetic process

PMID:8432721[4]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0003824

catalytic activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR007197
InterPro:IPR013785

F

Seeded From UniProt

complete

enables

GO:0005506

iron ion binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR012726

F

Seeded From UniProt

complete

involved_in

GO:0009228

thiamine biosynthetic process

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR012726

P

Seeded From UniProt

complete

enables

GO:0051536

iron-sulfur cluster binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR007197

F

Seeded From UniProt

complete

enables

GO:0051539

4 iron, 4 sulfur cluster binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR012726

F

Seeded From UniProt

complete

enables

GO:0036355

2-iminoacetate synthase activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:4.1.99.19

F

Seeded From UniProt

complete

enables

GO:0051539

4 iron, 4 sulfur cluster binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0004

F

Seeded From UniProt

complete

enables

GO:0051536

iron-sulfur cluster binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0411

F

Seeded From UniProt

complete

enables

GO:0046872

metal ion binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0479

F

Seeded From UniProt

complete

involved_in

GO:0009228

thiamine biosynthetic process

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0784

P

Seeded From UniProt

complete

enables

GO:0016829

lyase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0456

F

Seeded From UniProt

complete

involved_in

GO:0009229

thiamine diphosphate biosynthetic process

GO_REF:0000041

ECO:0000322

imported manually asserted information used in automatic assertion

UniPathway:UPA00060

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Khil, PP & Camerini-Otero, RD (2002) Over 1000 genes are involved in the DNA damage response of Escherichia coli. Mol. Microbiol. 44 89-105 PubMed GONUTS page
  2. Kriek, M et al. (2007) Thiazole synthase from Escherichia coli: an investigation of the substrates and purified proteins required for activity in vitro. J. Biol. Chem. 282 17413-23 PubMed GONUTS page
  3. Challand, MR et al. (2010) Catalytic activity of the anaerobic tyrosine lyase required for thiamine biosynthesis in Escherichia coli. J. Biol. Chem. 285 5240-8 PubMed GONUTS page
  4. Vander Horn, PB et al. (1993) Structural genes for thiamine biosynthetic enzymes (thiCEFGH) in Escherichia coli K-12. J. Bacteriol. 175 982-92 PubMed GONUTS page