GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.

Have any questions? Please email us at ecoliwiki@gmail.com

ECOLI:THIF

From GONUTS
Jump to: navigation, search
Species (Taxon ID) Escherichia coli (strain K12). (83333)
Gene Name(s) thiF
Protein Name(s) Sulfur carrier protein ThiS adenylyltransferase
External Links
UniProt P30138
EMBL M88701
U00006
U00096
AP009048
PIR C65206
RefSeq NP_418420.4
YP_491468.1
PDB 1ZFN
1ZKM
1ZUD
PDBsum 1ZFN
1ZKM
1ZUD
ProteinModelPortal P30138
SMR P30138
IntAct P30138
STRING 511145.b3992
PaxDb P30138
PRIDE P30138
EnsemblBacteria AAC76966
BAE77327
GeneID 12933663
948500
KEGG ecj:Y75_p3204
eco:b3992
PATRIC 32123507
EchoBASE EB1546
EcoGene EG11587
eggNOG COG0476
HOGENOM HOG000281217
InParanoid P30138
KO K03148
OMA DEPQRNC
OrthoDB EOG628F8J
PhylomeDB P30138
BioCyc EcoCyc:THIF-MONOMER
ECOL316407:JW3956-MONOMER
MetaCyc:THIF-MONOMER
UniPathway UPA00060
EvolutionaryTrace P30138
PRO PR:P30138
Proteomes UP000000318
UP000000625
Genevestigator P30138
GO GO:0005829
GO:0005524
GO:0000287
GO:0046872
GO:0016779
GO:0008270
GO:0006464
GO:0009228
GO:0009229
Gene3D 3.40.50.720
InterPro IPR012731
IPR007901
IPR009036
IPR016040
IPR000594
Pfam PF05237
PF00899
SUPFAM SSF69572
TIGRFAMs TIGR02356

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

enables

GO:0016779

nucleotidyltransferase activity

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

EcoGene:EG11587
PANTHER:PTN000102608

F

Seeded From UniProt

complete

part_of

GO:0005829

cytosol

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

EcoGene:EG10154
EcoGene:EG11587
PANTHER:PTN000102608

C

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

EcoGene:EG10154
EcoGene:EG11587
FB:FBgn0029113
FB:FBgn0032054
MGI:MGI:1921494
PANTHER:PTN000102040
PomBase:SPBC1604.21c
SGD:S000001214
SGD:S000001693
SGD:S000006384
TAIR:locus:2060854
TAIR:locus:2152375
TAIR:locus:2164270
TAIR:locus:2207185
UniProtKB:A0AVT1
UniProtKB:O95352
UniProtKB:O95396
UniProtKB:P42744
UniProtKB:Q8I5F9
UniProtKB:Q8ID54
UniProtKB:Q8IDZ6
UniProtKB:Q9GZZ9
UniProtKB:Q9SJT1
UniProtKB:Q9ZV69
WB:WBGene00004341
dictyBase:DDB_G0271096

C

Seeded From UniProt

complete

enables

GO:0046872

metal ion binding

PMID:16388576[2]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0016779

nucleotidyltransferase activity

PMID:9632726[3]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0008270

zinc ion binding

PMID:16388576[2]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

part_of

GO:0005829

cytosol

PMID:18304323[4]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

enables

GO:0005524

ATP binding

PMID:15896804[5]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0000287

magnesium ion binding

PMID:9632726[3]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0008641

ubiquitin-like modifier activating enzyme activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000594
InterPro:IPR035985

F

Seeded From UniProt

complete

enables

GO:0016740

transferase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0808

F

Seeded From UniProt

complete

enables

GO:0046872

metal ion binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0479

F

Seeded From UniProt

complete

enables

GO:0005524

ATP binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0067

F

Seeded From UniProt

complete

involved_in

GO:0009228

thiamine biosynthetic process

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0784

P

Seeded From UniProt

complete

enables

GO:0016779

nucleotidyltransferase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0548

F

Seeded From UniProt

complete

enables

GO:0000166

nucleotide binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0547

F

Seeded From UniProt

complete

involved_in

GO:0009229

thiamine diphosphate biosynthetic process

GO_REF:0000041

ECO:0000322

imported manually asserted information used in automatic assertion

UniPathway:UPA00060

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
  2. 2.0 2.1 Lehmann, C et al. (2006) Structure of the Escherichia coli ThiS-ThiF complex, a key component of the sulfur transfer system in thiamin biosynthesis. Biochemistry 45 11-9 PubMed GONUTS page
  3. 3.0 3.1 Taylor, SV et al. (1998) Thiamin biosynthesis in Escherichia coli. Identification of ThiS thiocarboxylate as the immediate sulfur donor in the thiazole formation. J. Biol. Chem. 273 16555-60 PubMed GONUTS page
  4. Ishihama, Y et al. (2008) Protein abundance profiling of the Escherichia coli cytosol. BMC Genomics 9 102 PubMed GONUTS page
  5. Duda, DM et al. (2005) Structural analysis of Escherichia coli ThiF. J. Mol. Biol. 349 774-86 PubMed GONUTS page