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ECOLI:THIE

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Species (Taxon ID) Escherichia coli (strain K12). (83333)
Gene Name(s) thiE
Protein Name(s) Thiamine-phosphate synthase

TP synthase TPS Thiamine-phosphate pyrophosphorylase TMP pyrophosphorylase TMP-PPase

External Links
UniProt P30137
EMBL M88701
U00006
U00096
AP009048
PIR S35118
RefSeq NP_418421.1
YP_491467.1
ProteinModelPortal P30137
SMR P30137
DIP DIP-10983N
IntAct P30137
MINT MINT-1247897
STRING 511145.b3993
SWISS-2DPAGE P30137
EnsemblBacteria AAC76967
BAE77326
GeneID 12930339
948491
KEGG ecj:Y75_p3203
eco:b3993
PATRIC 32123509
EchoBASE EB1545
EcoGene EG11586
eggNOG COG0352
HOGENOM HOG000155781
InParanoid P30137
KO K00788
OMA AVKHQAY
OrthoDB EOG6XWV53
PhylomeDB P30137
BioCyc EcoCyc:THIE-MONOMER
ECOL316407:JW3957-MONOMER
MetaCyc:THIE-MONOMER
UniPathway UPA00060
PRO PR:P30137
Proteomes UP000000318
UP000000625
Genevestigator P30137
GO GO:0000287
GO:0046872
GO:0004789
GO:0009228
GO:0009229
Gene3D 3.20.20.70
HAMAP MF_00097
InterPro IPR013785
IPR022998
IPR003733
Pfam PF02581
SUPFAM SSF51391
TIGRFAMs TIGR00693

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0009228

thiamine biosynthetic process

PMID:8432721[1]

ECO:0000315

P

Figure 3

complete
CACAO 4984

involved_in

GO:0009228

thiamine biosynthetic process

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

EcoGene:EG11586
PANTHER:PTN000466113
SGD:S000006135

P

Seeded From UniProt

complete

enables

GO:0004789

thiamine-phosphate diphosphorylase activity

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

EcoGene:EG11586
PANTHER:PTN000466113
SGD:S000006135

F

Seeded From UniProt

complete

enables

GO:0046872

metal ion binding

PMID:4580841[3]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0009228

thiamine biosynthetic process

PMID:10382260[4]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0000287

magnesium ion binding

PMID:4580841[3]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0003824

catalytic activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR013785

F

Seeded From UniProt

complete

enables

GO:0004789

thiamine-phosphate diphosphorylase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR034291

F

Seeded From UniProt

complete

involved_in

GO:0009228

thiamine biosynthetic process

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR034291

P

Seeded From UniProt

complete

enables

GO:0004789

thiamine-phosphate diphosphorylase activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:2.5.1.3

F

Seeded From UniProt

complete

involved_in

GO:0009228

thiamine biosynthetic process

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000076356

P

Seeded From UniProt

complete

enables

GO:0004789

thiamine-phosphate diphosphorylase activity

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000076356

F

Seeded From UniProt

complete

enables

GO:0000287

magnesium ion binding

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000076356

F

Seeded From UniProt

complete

involved_in

GO:0009228

thiamine biosynthetic process

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0784

P

Seeded From UniProt

complete

enables

GO:0046872

metal ion binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0479

F

Seeded From UniProt

complete

enables

GO:0016740

transferase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0808

F

Seeded From UniProt

complete

involved_in

GO:0009229

thiamine diphosphate biosynthetic process

GO_REF:0000041

ECO:0000322

imported manually asserted information used in automatic assertion

UniPathway:UPA00060

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Vander Horn, PB et al. (1993) Structural genes for thiamine biosynthetic enzymes (thiCEFGH) in Escherichia coli K-12. J. Bacteriol. 175 982-92 PubMed GONUTS page
  2. 2.0 2.1 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
  3. 3.0 3.1 Kayama, Y & Kawasaki, T (1973) Purification and properties of thiaminephosphate pyrophosphorylase of Escherichia coli. Arch. Biochem. Biophys. 158 242-8 PubMed GONUTS page
  4. Begley, TP et al. (1999) Thiamin biosynthesis in prokaryotes. Arch. Microbiol. 171 293-300 PubMed GONUTS page