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ECOLI:THD1
Contents
| Species (Taxon ID) | Escherichia coli (strain K12). (83333) | |
| Gene Name(s) | ilvA | |
| Protein Name(s) | L-threonine dehydratase biosynthetic IlvA
Threonine deaminase | |
| External Links | ||
| UniProt | P04968 | |
| EMBL | X04890 K03503 M10313 M11689 M32253 M87049 U00096 AP009048 M25497 | |
| PIR | B27310 | |
| RefSeq | NP_418220.1 YP_491666.1 | |
| PDB | 1TDJ | |
| PDBsum | 1TDJ | |
| ProteinModelPortal | P04968 | |
| SMR | P04968 | |
| DIP | DIP-10018N | |
| IntAct | P04968 | |
| MINT | MINT-1305200 | |
| STRING | 511145.b3772 | |
| PaxDb | P04968 | |
| PRIDE | P04968 | |
| EnsemblBacteria | AAC77492 BAE77525 | |
| GeneID | 12930592 948287 | |
| KEGG | ecj:Y75_p3403 eco:b3772 | |
| PATRIC | 32123039 | |
| EchoBASE | EB0488 | |
| EcoGene | EG10493 | |
| eggNOG | COG1171 | |
| HOGENOM | HOG000046975 | |
| InParanoid | P04968 | |
| KO | K01754 | |
| OMA | AHCFELC | |
| OrthoDB | EOG6ZSP7D | |
| PhylomeDB | P04968 | |
| BioCyc | EcoCyc:THREDEHYDSYN-MONOMER ECOL316407:JW3745-MONOMER MetaCyc:THREDEHYDSYN-MONOMER | |
| UniPathway | UPA00047 | |
| EvolutionaryTrace | P04968 | |
| PRO | PR:P04968 | |
| Proteomes | UP000000318 UP000000625 | |
| Genevestigator | P04968 | |
| GO | GO:0005737 GO:0016597 GO:0004794 GO:0030170 GO:0009082 GO:0009097 GO:0006566 | |
| InterPro | IPR001721 IPR000634 IPR005787 IPR001926 | |
| Pfam | PF00291 PF00585 | |
| SUPFAM | SSF53686 | |
| TIGRFAMs | TIGR01124 | |
| PROSITE | PS51672 PS00165 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
|
enables |
GO:0030170 |
pyridoxal phosphate binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006566 |
threonine metabolic process |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0009097 |
isoleucine biosynthetic process |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
EcoGene:EG10493 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0006567 |
threonine catabolic process |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN002463966 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0006566 |
threonine metabolic process |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
EcoGene:EG10493 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0004794 |
L-threonine ammonia-lyase activity |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
EcoGene:EG10493 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0016597 |
amino acid binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0009097 |
isoleucine biosynthetic process |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0009097 |
isoleucine biosynthetic process |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0009082 |
branched-chain amino acid biosynthetic process |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004794 |
L-threonine ammonia-lyase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004794 |
L-threonine ammonia-lyase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004794 |
L-threonine ammonia-lyase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0030170 |
pyridoxal phosphate binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0009097 |
isoleucine biosynthetic process |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004794 |
L-threonine ammonia-lyase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004794 |
L-threonine ammonia-lyase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006520 |
cellular amino acid metabolic process |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0009097 |
isoleucine biosynthetic process |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0030170 |
pyridoxal phosphate binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004794 |
L-threonine ammonia-lyase activity |
ECO:0000501 |
evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0008152 |
metabolic process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0009082 |
branched-chain amino acid biosynthetic process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003824 |
catalytic activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016829 |
lyase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0008652 |
cellular amino acid biosynthetic process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0009097 |
isoleucine biosynthetic process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
UniProtKB-KW:KW-0412 |
P |
Seeded From UniProt |
complete | ||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Phillips, AT & Wood, WA (1965) The mechanism of action of 5'-adenylic acid-activated threonine dehydrase. J. Biol. Chem. 240 4703-9 PubMed GONUTS page
- ↑ UMBARGER, HE & BROWN, B (1957) Threonine deamination in Escherichia coli. II. Evidence for two L-threonine deaminases. J. Bacteriol. 73 105-12 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 3.3 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
- ↑ 4.0 4.1 4.2 Eisenstein, E (1991) Cloning, expression, purification, and characterization of biosynthetic threonine deaminase from Escherichia coli. J. Biol. Chem. 266 5801-7 PubMed GONUTS page
- ↑ 5.0 5.1 Fisher, KE & Eisenstein, E (1993) An efficient approach to identify ilvA mutations reveals an amino-terminal catalytic domain in biosynthetic threonine deaminase from Escherichia coli. J. Bacteriol. 175 6605-13 PubMed GONUTS page
- ↑ 6.0 6.1 Favre, R et al. (1974) Complementation between different mutations in the ilvA gene of Escherichia coli K-12. J. Bacteriol. 119 1069-71 PubMed GONUTS page
- ↑ Williams, AL et al. (1978) Synthesis and activities of branched-chain aminoacyl-tRNA synthetases in threonine deaminase mutants of Escherichia coli. J. Bacteriol. 134 92-9 PubMed GONUTS page
- ↑ 8.0 8.1 Calhoun, DH et al. (1973) Threonine deaminase from Escherichia coli. I. Purification and properties. J. Biol. Chem. 248 3511-6 PubMed GONUTS page
