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ECOLI:SOXR
Contents
| Species (Taxon ID) | Escherichia coli (strain K12). (83333) | |
| Gene Name(s) | soxR (synonyms: marC) | |
| Protein Name(s) | Redox-sensitive transcriptional activator SoxR | |
| External Links | ||
| UniProt | P0ACS2 | |
| EMBL | M60111 X59593 U00006 U00096 AP009048 S72675 | |
| PIR | JS0577 | |
| RefSeq | NP_418487.1 YP_492206.1 | |
| PDB | 2ZHG 2ZHH | |
| PDBsum | 2ZHG 2ZHH | |
| ProteinModelPortal | P0ACS2 | |
| SMR | P0ACS2 | |
| DIP | DIP-29848N | |
| IntAct | P0ACS2 | |
| STRING | 511145.b4063 | |
| PRIDE | P0ACS2 | |
| EnsemblBacteria | AAC77033 BAE78065 | |
| GeneID | 12930607 948566 | |
| KEGG | ecj:Y75_p3950 eco:b4063 | |
| PATRIC | 32123671 | |
| EchoBASE | EB0950 | |
| EcoGene | EG10957 | |
| eggNOG | COG0789 | |
| HOGENOM | HOG000266085 | |
| InParanoid | P0ACS2 | |
| KO | K13639 | |
| OMA | IHFYEAK | |
| OrthoDB | EOG600DQR | |
| PhylomeDB | P0ACS2 | |
| BioCyc | EcoCyc:PD04132 ECOL316407:JW4024-MONOMER RETL1328306-WGS:GSTH-3949-MONOMER | |
| EvolutionaryTrace | P0ACS2 | |
| PRO | PR:P0ACS2 | |
| Proteomes | UP000000318 UP000000625 | |
| Genevestigator | P0ACS2 | |
| GO | GO:0005737 GO:0051537 GO:0003677 GO:0046872 GO:0006355 GO:0006979 GO:0006351 | |
| InterPro | IPR009061 IPR000551 IPR010211 IPR015358 | |
| PANTHER | PTHR30204:SF0 | |
| Pfam | PF00376 PF09278 | |
| PRINTS | PR00040 | |
| SMART | SM00422 | |
| SUPFAM | SSF46955 | |
| TIGRFAMs | TIGR01950 | |
| PROSITE | PS00552 PS50937 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
|
enables |
GO:0051537 |
2 iron, 2 sulfur cluster binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006979 |
response to oxidative stress |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
| GO:0006979 |
response to oxidative stress |
PMID:PMC207867 |
ECO:0000315 |
P |
figure 4 shows phenotypic changes upon nucleotide deletion |
complete | ||||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003677 |
DNA binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006355 |
regulation of transcription, DNA-templated |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006979 |
response to oxidative stress |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0051537 |
2 iron, 2 sulfur cluster binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0046872 |
metal ion binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0051537 |
2 iron, 2 sulfur cluster binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0051536 |
iron-sulfur cluster binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003677 |
DNA binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
Contributes to |
GO:0006979 |
response to oxidative stress |
ECO:0000315 |
P |
Figure:3 e and f, shows mutant gene soxR untreated and ozone treated |
complete | ||||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Gaudu, P et al. (1997) Regulation of the soxRS oxidative stress regulon. Reversible oxidation of the Fe-S centers of SoxR in vivo. J. Biol. Chem. 272 5082-6 PubMed GONUTS page
- ↑ Greenberg, JT et al. (1990) Positive control of a global antioxidant defense regulon activated by superoxide-generating agents in Escherichia coli. Proc. Natl. Acad. Sci. U.S.A. 87 6181-5 PubMed GONUTS page
- ↑ Patil, S et al. (2011) Assessing the microbial oxidative stress mechanism of ozone treatment through the responses of Escherichia coli mutants. J. Appl. Microbiol. 111 136-44 PubMed GONUTS page
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