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ECOLI:SBCD

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Species (Taxon ID) Escherichia coli (strain K12). (83333)
Gene Name(s) sbcD (synonyms: yajA)
Protein Name(s) Nuclease SbcCD subunit D
External Links
UniProt P0AG76
EMBL X15981
U73857
U00096
AP009048
PIR JS0349
RefSeq NP_414932.1
WP_001221319.1
ProteinModelPortal P0AG76
SMR P0AG76
DIP DIP-10828N
IntAct P0AG76
STRING 511145.b0398
PaxDb P0AG76
EnsemblBacteria AAC73501
BAE76178
GeneID 945049
KEGG ecj:JW0388
eco:b0398
PATRIC 32115939
EchoBASE EB1086
EcoGene EG11094
eggNOG ENOG4107RH8
COG0420
HOGENOM HOG000026261
InParanoid P0AG76
KO K03547
OMA DAFDTVN
OrthoDB EOG60CWP4
PhylomeDB P0AG76
BioCyc EcoCyc:EG11094-MONOMER
ECOL316407:JW0388-MONOMER
PRO PR:P0AG76
Proteomes UP000000318
UP000000625
GO GO:0008408
GO:0004519
GO:0006259
GO:0006310
GO:0006260
Gene3D 3.60.21.10
InterPro IPR004843
IPR029052
IPR004593
IPR026843
Pfam PF00149
PF12320
SUPFAM SSF56300
TIGRFAMs TIGR00619

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

enables

GO:1990238

double-stranded DNA endodeoxyribonuclease activity

PMID:9653124[1]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0006281

DNA repair

PMID:18342610[2]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0004529

exodeoxyribonuclease activity

PMID:9133662[3]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0000014

single-stranded DNA endodeoxyribonuclease activity

PMID:9133662[3]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0090305

nucleic acid phosphodiester bond hydrolysis

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0008408

P

Seeded From UniProt

complete

involved_in

GO:0090305

nucleic acid phosphodiester bond hydrolysis

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0004519

P

Seeded From UniProt

complete

involved_in

GO:0090305

nucleic acid phosphodiester bond hydrolysis

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0004527

P

Seeded From UniProt

complete

involved_in

GO:0090305

nucleic acid phosphodiester bond hydrolysis

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0004518

P

Seeded From UniProt

complete

enables

GO:0004519

endonuclease activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR004593

F

Seeded From UniProt

complete

involved_in

GO:0006259

DNA metabolic process

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR004593

P

Seeded From UniProt

complete

enables

GO:0008408

3'-5' exonuclease activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR004593

F

Seeded From UniProt

complete

enables

GO:0016787

hydrolase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR004843

F

Seeded From UniProt

complete

enables

GO:0016787

hydrolase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0378

F

Seeded From UniProt

complete

enables

GO:0004527

exonuclease activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0269

F

Seeded From UniProt

complete

enables

GO:0004519

endonuclease activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0255

F

Seeded From UniProt

complete

enables

GO:0004518

nuclease activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0540

F

Seeded From UniProt

complete

involved_in

GO:0006260

DNA replication

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0235

P

Seeded From UniProt

complete

involved_in

GO:0006310

DNA recombination

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0233

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Connelly, JC et al. (1998) The SbcCD nuclease of Escherichia coli is a structural maintenance of chromosomes (SMC) family protein that cleaves hairpin DNA. Proc. Natl. Acad. Sci. U.S.A. 95 7969-74 PubMed GONUTS page
  2. Eykelenboom, JK et al. (2008) SbcCD causes a double-strand break at a DNA palindrome in the Escherichia coli chromosome. Mol. Cell 29 644-51 PubMed GONUTS page
  3. 3.0 3.1 Connelly, JC & Leach, DR (1996) The sbcC and sbcD genes of Escherichia coli encode a nuclease involved in palindrome inviability and genetic recombination. Genes Cells 1 285-91 PubMed GONUTS page