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ECOLI:RSEA
Contents
| Species (Taxon ID) | Escherichia coli (strain K12). (83333) | |
| Gene Name(s) | rseA (synonyms: mclA, yfiJ) | |
| Protein Name(s) | Anti-sigma-E factor RseA
Regulator of SigE Sigma-E anti-sigma factor RseA Sigma-E factor negative regulatory protein | |
| External Links | ||
| UniProt | P0AFX7 | |
| EMBL | U10148 U37089 D64044 D13169 U00096 AP009048 U37455 | |
| PIR | B57255 | |
| RefSeq | NP_417067.1 YP_490800.1 | |
| PDB | 1OR7 1YFN 3M4W | |
| PDBsum | 1OR7 1YFN 3M4W | |
| DisProt | DP00552 | |
| ProteinModelPortal | P0AFX7 | |
| SMR | P0AFX7 | |
| DIP | DIP-39581N | |
| IntAct | P0AFX7 | |
| STRING | 511145.b2572 | |
| EnsemblBacteria | AAC75625 BAE76748 | |
| GeneID | 12932970 947053 | |
| KEGG | ecj:Y75_p2525 eco:b2572 | |
| PATRIC | 32120543 | |
| EchoBASE | EB2245 | |
| EcoGene | EG12341 | |
| eggNOG | COG3073 | |
| HOGENOM | HOG000272262 | |
| InParanoid | P0AFX7 | |
| KO | K03597 | |
| OMA | QNQSYTN | |
| OrthoDB | EOG6V7BSG | |
| BioCyc | EcoCyc:EG12341-MONOMER ECOL316407:JW2556-MONOMER | |
| EvolutionaryTrace | P0AFX7 | |
| PRO | PR:P0AFX7 | |
| Proteomes | UP000000318 UP000000625 | |
| Genevestigator | P0AFX7 | |
| GO | GO:0016021 GO:0005886 GO:0016989 GO:0006355 GO:0006950 GO:0006351 | |
| InterPro | IPR005573 IPR005572 IPR026279 | |
| Pfam | PF03873 PF03872 | |
| PIRSF | PIRSF016938 | |
| SUPFAM | SSF89069 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
| GO:0031333 |
negative regulation of protein complex assembly |
ECO:0000315 |
P |
Fig 3: reintroduction of negative regulator RseA restores growth and envelope stress response in bam mutants |
complete | |||||
|
enables |
GO:0016989 |
sigma factor antagonist activity |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
EcoGene:EG12341 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0016989 |
sigma factor antagonist activity |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005887 |
integral component of plasma membrane |
ECO:0000245 |
automatically integrated combinatorial evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:1903507 |
negative regulation of nucleic acid-templated transcription |
ECO:0000366 |
evidence based on logical inference from automatic annotation used in automatic assertion |
GO:0016989 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:1903507 |
negative regulation of nucleic acid-templated transcription |
ECO:0000364 |
evidence based on logical inference from manual annotation used in automatic assertion |
GO:0016989 |
P |
Seeded From UniProt |
complete | ||
| GO:0005886 |
plasma membrane |
ECO:0000314 |
C |
Figure 5 shows localization of RseA fragments in the inner membrane of E. coli via Western Blot analysis. |
complete | |||||
|
involved_in |
GO:1903507 |
negative regulation of nucleic acid-templated transcription |
ECO:0000364 |
evidence based on logical inference from manual annotation used in automatic assertion |
GO:0016989 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0016989 |
sigma factor antagonist activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005886 |
plasma membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
UniProtKB-KW:KW-1003 |
C |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0016021 |
integral component of membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016020 |
membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Gerken, H et al. (2010) Involvement and necessity of the Cpx regulon in the event of aberrant beta-barrel outer membrane protein assembly. Mol. Microbiol. 75 1033-46 PubMed GONUTS page
- ↑ Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
- ↑ Missiakas, D et al. (1997) Modulation of the Escherichia coli sigmaE (RpoE) heat-shock transcription-factor activity by the RseA, RseB and RseC proteins. Mol. Microbiol. 24 355-71 PubMed GONUTS page
- ↑ Lomize, AL et al. (2017) Membranome: a database for proteome-wide analysis of single-pass membrane proteins. Nucleic Acids Res. 45 D250-D255 PubMed GONUTS page
- ↑ Alba, BM et al. (2002) DegS and YaeL participate sequentially in the cleavage of RseA to activate the sigma(E)-dependent extracytoplasmic stress response. Genes Dev. 16 2156-68 PubMed GONUTS page
b
