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ECOLI:RP5M

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Species (Taxon ID) Escherichia coli (strain K12). (83333)
Gene Name(s) hpf (synonyms: yhbH)
Protein Name(s) Ribosome hibernation promoting factor
External Links
UniProt P0AFX0
EMBL D12938
Z27094
U12684
U18997
U00096
AP009048
PIR I76719
RefSeq NP_417670.1
YP_491388.1
PDB 2RQL
4V8H
PDBsum 2RQL
4V8H
ProteinModelPortal P0AFX0
SMR P0AFX0
DIP DIP-48273N
IntAct P0AFX0
MINT MINT-1249576
STRING 511145.b3203
PaxDb P0AFX0
PRIDE P0AFX0
EnsemblBacteria AAC76235
BAE77247
GeneID 12930289
947718
KEGG ecj:Y75_p3123
eco:b3203
PATRIC 32121826
EchoBASE EB1632
EcoGene EG11681
eggNOG COG1544
HOGENOM HOG000264773
InParanoid P0AFX0
KO K05808
OMA NLTGHHI
OrthoDB EOG618R0J
PhylomeDB P0AFX0
BioCyc EcoCyc:EG11681-MONOMER
ECOL316407:JW3170-MONOMER
EvolutionaryTrace P0AFX0
PRO PR:P0AFX0
Proteomes UP000000318
UP000000625
Genevestigator P0AFX0
GO GO:0043024
GO:0043022
GO:0017148
GO:0044238
Gene3D 3.30.160.100
InterPro IPR003489
Pfam PF02482
SUPFAM SSF69754
TIGRFAMs TIGR00741

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0031118

rRNA pseudouridine synthesis

PMID:16324148[1]

ECO:0000315

P

Figure 2. YhbH converts immature 90S particles to mature 100S ribosomal particles by promoting both particle formation and stabilization.

complete

involved_in

GO:0045900

negative regulation of translational elongation

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

EcoGene:EG11151
PANTHER:PTN002114317

P

Seeded From UniProt

complete

enables

GO:0043024

ribosomal small subunit binding

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

EcoGene:EG11151
EcoGene:EG11681
PANTHER:PTN002114317

F

Seeded From UniProt

complete

enables

GO:0043022

ribosome binding

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

EcoGene:EG11681
PANTHER:PTN002114317

F

Seeded From UniProt

complete

part_of

GO:0022627

cytosolic small ribosomal subunit

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

EcoGene:EG11151
PANTHER:PTN002114317

C

Seeded From UniProt

complete

enables

GO:0043024

ribosomal small subunit binding

PMID:22605777[3]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0043022

ribosome binding

PMID:11168583[4]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0017148

negative regulation of translation

PMID:18174192[5]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0005829

cytosol

PMID:18304323[6]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0044238

primary metabolic process

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR003489

P

Seeded From UniProt

complete

involved_in

GO:0006417

regulation of translation

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0810

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Ueta, M et al. (2005) Ribosome binding proteins YhbH and YfiA have opposite functions during 100S formation in the stationary phase of Escherichia coli. Genes Cells 10 1103-12 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
  3. Polikanov, YS et al. (2012) How hibernation factors RMF, HPF, and YfiA turn off protein synthesis. Science 336 915-8 PubMed GONUTS page
  4. Maki, Y et al. (2000) Two proteins, YfiA and YhbH, associated with resting ribosomes in stationary phase Escherichia coli. Genes Cells 5 965-74 PubMed GONUTS page
  5. Ueta, M et al. (2008) Role of HPF (hibernation promoting factor) in translational activity in Escherichia coli. J. Biochem. 143 425-33 PubMed GONUTS page
  6. Ishihama, Y et al. (2008) Protein abundance profiling of the Escherichia coli cytosol. BMC Genomics 9 102 PubMed GONUTS page