ECOLI:RNH

Species (Taxon ID)	Escherichia coli (strain K12). (83333)
Gene Name(s)	rnhA (synonyms: dasF, herA, rnh, sdrA)
Protein Name(s)	Ribonuclease HI RNase HI Ribonuclease H RNase H
External Links
UniProt	P0A7Y4
EMBL	K00985 V00337 X04027 U70214 U00096 AP009048
PIR	A92401
RefSeq	NP_414750.1 YP_488511.1
PDB	1F21 1G15 1GOA 1GOB 1GOC 1JL1 1JL2 1JXB 1KVA 1KVB 1KVC 1LAV 1LAW 1RBR 1RBS 1RBT 1RBU 1RBV 1RCH 1RDA 1RDB 1RDC 1RDD 1RNH 1WSE 1WSF 1WSG 1WSH 1WSI 1WSJ 2RN2 2YV0 2Z1G 2Z1H 2Z1I 2Z1J 3AA2 3AA3 3AA4 3AA5 3HYF 3QIN 3QIO
PDBsum	1F21 1G15 1GOA 1GOB 1GOC 1JL1 1JL2 1JXB 1KVA 1KVB 1KVC 1LAV 1LAW 1RBR 1RBS 1RBT 1RBU 1RBV 1RCH 1RDA 1RDB 1RDC 1RDD 1RNH 1WSE 1WSF 1WSG 1WSH 1WSI 1WSJ 2RN2 2YV0 2Z1G 2Z1H 2Z1I 2Z1J 3AA2 3AA3 3AA4 3AA5 3HYF 3QIN 3QIO
ProteinModelPortal	P0A7Y4
SMR	P0A7Y4
DIP	DIP-47864N
IntAct	P0A7Y4
MINT	MINT-1224022
STRING	511145.b0214
BindingDB	P0A7Y4
ChEMBL	CHEMBL1770039
PaxDb	P0A7Y4
PRIDE	P0A7Y4
EnsemblBacteria	AAC73319 BAA77885
GeneID	12934461 946955
KEGG	ecj:Y75_p0205 eco:b0214
PATRIC	32115541
EchoBASE	EB0853
EcoGene	EG10860
eggNOG	COG0328
HOGENOM	HOG000040465
InParanoid	P0A7Y4
KO	K03469
OMA	ITSWIHN
OrthoDB	EOG696BTR
PhylomeDB	P0A7Y4
BioCyc	EcoCyc:EG10860-MONOMER ECOL316407:JW0204-MONOMER MetaCyc:EG10860-MONOMER
EvolutionaryTrace	P0A7Y4
PRO	PR:P0A7Y4
Proteomes	UP000000318 UP000000625
Genevestigator	P0A7Y4
GO	GO:0005737 GO:0004519 GO:0000287 GO:0003676 GO:0004523 GO:0043137 GO:0090305 GO:0090502
Gene3D	3.30.420.10
HAMAP	MF_00042
InterPro	IPR022892 IPR012337 IPR002156
Pfam	PF00075
SUPFAM	SSF53098
PROSITE	PS50879

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
	GO:0004523	ribonuclease H activity	PMID:4572736	ECO:0000314			F		See Fig 2	complete
involved_in	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000068227 WB:WBGene00004382 WB:WBGene00022888	P		Seeded From UniProt	complete
involved_in	GO:0043137	DNA replication, removal of RNA primer		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	EcoGene:EG10860 PANTHER:PTN000068227	P		Seeded From UniProt	complete
enables	GO:0004523	RNA-DNA hybrid ribonuclease activity		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	EcoGene:EG10860 FB:FBgn0023171 MGI:MGI:1335073 PANTHER:PTN000068227 PomBase:SPBC336.06c SGD:S000004847 UniProtKB:O60930 WB:WBGene00004382 WB:WBGene00022888	F		Seeded From UniProt	complete
enables	GO:0004523	RNA-DNA hybrid ribonuclease activity	PMID:4572736	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
enables	GO:0004519	endonuclease activity	PMID:4572736	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
enables	GO:0003676	nucleic acid binding	PMID:4572736	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
involved_in	GO:0043137	DNA replication, removal of RNA primer	PMID:6319961	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
enables	GO:0004523	RNA-DNA hybrid ribonuclease activity	PMID:4572736	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
enables	GO:0004523	RNA-DNA hybrid ribonuclease activity	PMID:25903123	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
enables	GO:0003676	nucleic acid binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR002156 InterPro:IPR036397	F		Seeded From UniProt	complete
enables	GO:0004523	RNA-DNA hybrid ribonuclease activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR002156 InterPro:IPR022892	F		Seeded From UniProt	complete
enables	GO:0004523	RNA-DNA hybrid ribonuclease activity	GO_REF:0000003	ECO:0000501	evidence used in automatic assertion	EC:3.1.26.4	F		Seeded From UniProt	complete
enables	GO:0000287	magnesium ion binding	GO_REF:0000104	ECO:0000256	match to sequence model evidence used in automatic assertion	UniRule:UR000075854	F		Seeded From UniProt	complete
enables	GO:0004523	RNA-DNA hybrid ribonuclease activity	GO_REF:0000104	ECO:0000256	match to sequence model evidence used in automatic assertion	UniRule:UR000075854	F		Seeded From UniProt	complete
involved_in	GO:0006401	RNA catabolic process	GO_REF:0000104	ECO:0000256	match to sequence model evidence used in automatic assertion	UniRule:UR000075854	P		Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000104	ECO:0000256	match to sequence model evidence used in automatic assertion	UniRule:UR000075854	C		Seeded From UniProt	complete
enables	GO:0004518	nuclease activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0540	F		Seeded From UniProt	complete
enables	GO:0004519	endonuclease activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0255	F		Seeded From UniProt	complete
enables	GO:0046872	metal ion binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0479	F		Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0963 UniProtKB-SubCell:SL-0086	C		Seeded From UniProt	complete
enables	GO:0016787	hydrolase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0378	F		Seeded From UniProt	complete
edit table

References

See Help:References for how to manage references in GONUTS.