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ECOLI:RFAQ

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Species (Taxon ID) Escherichia coli (strain K12). (83333)
Gene Name(s) rfaQ (synonyms: waaQ)
Protein Name(s) Lipopolysaccharide core heptosyltransferase RfaQ
External Links
UniProt P25742
EMBL M80599
M86305
U00039
U00096
AP009048
PIR S27560
RefSeq NP_418089.1
YP_491801.1
ProteinModelPortal P25742
SMR P25742
DIP DIP-10675N
IntAct P25742
MINT MINT-1275410
STRING 511145.b3632
CAZy GT9
PRIDE P25742
EnsemblBacteria AAC76656
BAE77660
GeneID 12930601
948155
KEGG ecj:Y75_p3542
eco:b3632
PATRIC 32122751
EchoBASE EB1317
EcoGene EG11341
eggNOG COG0859
HOGENOM HOG000010798
InParanoid P25742
KO K02849
OMA SMPMHLA
OrthoDB EOG6DRPDK
PhylomeDB P25742
BioCyc EcoCyc:EG11341-MONOMER
ECOL316407:JW3607-MONOMER
MetaCyc:EG11341-MONOMER
UniPathway UPA00958
PRO PR:P25742
Proteomes UP000000318
UP000000625
Genevestigator P25742
GO GO:0016740
GO:0016757
GO:0009244
InterPro IPR002201
IPR011916
Pfam PF01075
TIGRFAMs TIGR02201

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0008920

lipopolysaccharide heptosyltransferase activity

PMID:9756860[1]

ECO:0000315

F

Figure 3 - Gas Chromatograph of core oligosaccharide. Compared to wildtype (3a), waaQ mutant (3c) is missing peak 6 (terminal heptose).

complete
CACAO 4667

GO:0009244

lipopolysaccharide core region biosynthetic process

PMID:9756860[1]

ECO:0000315

P

Figure 3 - Gas chromatograph of expressed core oligosaccharide. waaQ (3c) mutant expresses a truncated core, missing the terminal heptose (peak 6) as compared to wildtype (3a).

complete
CACAO 4668

involved_in

GO:0009244

lipopolysaccharide core region biosynthetic process

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

EcoGene:EG11189
EcoGene:EG11341
EcoGene:EG11423
EcoGene:EG12210
PANTHER:PTN001575314
UniProtKB:G3XD35
UniProtKB:P26469
UniProtKB:P37421
UniProtKB:Q9HUF5

P

Seeded From UniProt

complete

enables

GO:0008713

ADP-heptose-lipopolysaccharide heptosyltransferase activity

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

EcoGene:EG12210
PANTHER:PTN001575314

F

Seeded From UniProt

complete

part_of

GO:0005829

cytosol

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

EcoGene:EG12210
PANTHER:PTN001575314

C

Seeded From UniProt

complete

enables

GO:0071967

lipopolysaccharide core heptosyltransferase activity

PMID:25957775[3]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0009244

lipopolysaccharide core region biosynthetic process

PMID:9756860[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0016757

transferase activity, transferring glycosyl groups

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR002201

F

Seeded From UniProt

complete

involved_in

GO:0009103

lipopolysaccharide biosynthetic process

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0448

P

Seeded From UniProt

complete

enables

GO:0016757

transferase activity, transferring glycosyl groups

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0328

F

Seeded From UniProt

complete

enables

GO:0016740

transferase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0808

F

Seeded From UniProt

complete

involved_in

GO:0009244

lipopolysaccharide core region biosynthetic process

GO_REF:0000041

ECO:0000322

imported manually asserted information used in automatic assertion

UniPathway:UPA00958

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 Yethon, JA et al. (1998) Involvement of waaY, waaQ, and waaP in the modification of Escherichia coli lipopolysaccharide and their role in the formation of a stable outer membrane. J. Biol. Chem. 273 26310-6 PubMed GONUTS page
  2. 2.0 2.1 2.2 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
  3. Mudapaka, J & Taylor, EA (2015) Cloning and characterization of the Escherichia coli Heptosyltransferase III: Exploring substrate specificity in lipopolysaccharide core biosynthesis. FEBS Lett. 589 1423-9 PubMed GONUTS page