GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.
ECOLI:REP
Contents
| Species (Taxon ID) | Escherichia coli (strain K12). (83333) | |
| Gene Name(s) | rep (ECO:0000255 with HAMAP-Rule:MF_01920) | |
| Protein Name(s) | ATP-dependent DNA helicase Rep (ECO:0000255 with HAMAP-Rule:MF_01920) | |
| External Links | ||
| UniProt | P09980 | |
| EMBL | X04794 M87049 U00096 AP009048 M11055 | |
| PIR | E65181 | |
| RefSeq | YP_026251.1 YP_491661.1 | |
| PDB | 1UAA | |
| PDBsum | 1UAA | |
| ProteinModelPortal | P09980 | |
| SMR | P09980 | |
| DIP | DIP-10662N | |
| IntAct | P09980 | |
| MINT | MINT-1286362 | |
| STRING | 511145.b3778 | |
| PaxDb | P09980 | |
| PRIDE | P09980 | |
| EnsemblBacteria | AAT48209 BAE77520 | |
| GeneID | 12934323 948292 | |
| KEGG | ecj:Y75_p3397 eco:b3778 | |
| PATRIC | 32123047 | |
| EchoBASE | EB0830 | |
| EcoGene | EG10837 | |
| eggNOG | COG0210 | |
| HOGENOM | HOG000033015 | |
| InParanoid | P09980 | |
| KO | K03656 | |
| OMA | VLMQNRI | |
| OrthoDB | EOG64N9TW | |
| PhylomeDB | P09980 | |
| BioCyc | EcoCyc:EG10837-MONOMER ECOL316407:JW5604-MONOMER MetaCyc:EG10837-MONOMER | |
| EvolutionaryTrace | P09980 | |
| PRO | PR:P09980 | |
| Proteomes | UP000000318 UP000000625 | |
| Genevestigator | P09980 | |
| GO | GO:0005737 GO:0005524 GO:0004003 GO:0003677 GO:0006268 | |
| Gene3D | 1.10.10.160 3.40.50.300 | |
| HAMAP | MF_01920 | |
| InterPro | IPR013986 IPR005752 IPR014017 IPR000212 IPR027417 IPR014016 | |
| PANTHER | PTHR11070 | |
| Pfam | PF00580 PF13361 | |
| SUPFAM | SSF52540 | |
| TIGRFAMs | TIGR01074 | |
| PROSITE | PS51198 PS51217 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
| GO:0003678 |
DNA helicase activity |
ECO:0000247 |
|
F |
Figure 4 |
complete | ||||
|
enables |
GO:0043140 |
ATP-dependent 3'-5' DNA helicase activity |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
EcoGene:EG10426 |
F |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0006281 |
DNA repair |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
EcoGene:EG11064 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005829 |
cytosol |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
EcoGene:EG10426 |
C |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0000725 |
recombinational repair |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000116141 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0044787 |
bacterial-type DNA replication |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0044787 |
bacterial-type DNA replication |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0009314 |
response to radiation |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006268 |
DNA unwinding involved in DNA replication |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004003 |
ATP-dependent DNA helicase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0090305 |
nucleic acid phosphodiester bond hydrolysis |
ECO:0000366 |
evidence based on logical inference from automatic annotation used in automatic assertion |
GO:0008408 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0003677 |
DNA binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004003 |
ATP-dependent DNA helicase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0005524 |
ATP binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
InterPro:IPR000212 |
F |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0006268 |
DNA unwinding involved in DNA replication |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016787 |
hydrolase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003697 |
single-stranded DNA binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000161582 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0005524 |
ATP binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000161582 |
F |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0006268 |
DNA unwinding involved in DNA replication |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000161582 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0004003 |
ATP-dependent DNA helicase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000161582 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0008408 |
3'-5' exonuclease activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000161582 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0005524 |
ATP binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003677 |
DNA binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006260 |
DNA replication |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0000166 |
nucleotide binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004386 |
helicase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016787 |
hydrolase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Lohman, TM et al. (1989) Large-scale purification and characterization of the Escherichia coli rep gene product. J. Biol. Chem. 264 10139-47 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
- ↑ Lane, HE & Denhardt, DT (1974) The rep mutation. III. Altered structure of the replicating Escherichia coli chromosome. J. Bacteriol. 120 805-14 PubMed GONUTS page
- ↑ Lane, HE & Denhardt, DT (1975) The rep mutation. IV. Slower movement of replication forks in Escherichia coli rep strains. J. Mol. Biol. 97 99-112 PubMed GONUTS page
- ↑ Sargentini, NJ et al. () Screen for genes involved in radiation survival of Escherichia coli and construction of a reference database. Mutat. Res. 793-794 1-14 PubMed GONUTS page
- ↑ 6.0 6.1 Takahashi, S et al. (1979) The rep mutation. VI. Purification and properties of the Escherichia coli rep protein, DNA helicase III. Can. J. Biochem. 57 855-66 PubMed GONUTS page
a
d
o
