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ECOLI:RELA

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Species (Taxon ID) Escherichia coli (strain K12). (83333)
Gene Name(s) relA
Protein Name(s) GTP pyrophosphokinase

(p)ppGpp synthase ATP:GTP 3'-pyrophosphotransferase ppGpp synthase I

External Links
UniProt P0AG20
EMBL J04039
U29580
U00096
AP009048
PIR D65060
RefSeq NP_417264.1
YP_490992.1
ProteinModelPortal P0AG20
SMR P0AG20
DIP DIP-10658N
IntAct P0AG20
STRING 511145.b2784
ChEMBL CHEMBL1163114
PaxDb P0AG20
PRIDE P0AG20
EnsemblBacteria AAC75826
BAE76858
GeneID 12930232
947244
KEGG ecj:Y75_p2721
eco:b2784
PATRIC 32120984
EchoBASE EB0828
EcoGene EG10835
eggNOG COG0317
HOGENOM HOG000018300
InParanoid P0AG20
KO K00951
OMA SDIGHRC
OrthoDB EOG6SV551
PhylomeDB P0AG20
BioCyc EcoCyc:RELA-MONOMER
ECOL316407:JW2755-MONOMER
MetaCyc:RELA-MONOMER
UniPathway UPA00908
PRO PR:P0AG20
Proteomes UP000000318
UP000000625
Genevestigator P0AG20
GO GO:0016597
GO:0005524
GO:0005525
GO:0008728
GO:0016301
GO:0015970
GO:0015969
GO:0015949
Gene3D 3.10.20.30
InterPro IPR002912
IPR012675
IPR004811
IPR007685
IPR004095
IPR012676
Pfam PF01842
PF04607
PF02824
SMART SM00954
SUPFAM SSF81271
TIGRFAMs TIGR00691
PROSITE PS51671

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

involved_in

GO:0042594

response to starvation

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

EcoGene:EG10966
PANTHER:PTN001083175

P

Seeded From UniProt

complete

involved_in

GO:0015969

guanosine tetraphosphate metabolic process

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

EcoGene:EG10835
EcoGene:EG10966
PANTHER:PTN001083175

P

Seeded From UniProt

complete

enables

GO:0008893

guanosine-3',5'-bis(diphosphate) 3'-diphosphatase activity

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

EcoGene:EG10966
PANTHER:PTN001083175

F

Seeded From UniProt

complete

enables

GO:0008728

GTP diphosphokinase activity

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

EcoGene:EG10835
PANTHER:PTN001083175

F

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000479633
UniProtKB:P9WHG9

C

Seeded From UniProt

complete

part_of

GO:0005618

cell wall

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000479633
UniProtKB:P9WHG9

C

Seeded From UniProt

complete

involved_in

GO:0015969

guanosine tetraphosphate metabolic process

PMID:2556396[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0015949

nucleobase-containing small molecule interconversion

PMID:12419222[3]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0008728

GTP diphosphokinase activity

PMID:195816[4]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0015969

guanosine tetraphosphate metabolic process

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR004811
InterPro:IPR007685

P

Seeded From UniProt

complete

enables

GO:0008728

GTP diphosphokinase activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:2.7.6.5

F

Seeded From UniProt

complete

enables

GO:0005525

GTP binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0342

F

Seeded From UniProt

complete

enables

GO:0016301

kinase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0418

F

Seeded From UniProt

complete

involved_in

GO:0016310

phosphorylation

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0418

P

Seeded From UniProt

complete

enables

GO:0016740

transferase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0808

F

Seeded From UniProt

complete

enables

GO:0000166

nucleotide binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0547

F

Seeded From UniProt

complete

enables

GO:0005524

ATP binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0067

F

Seeded From UniProt

complete

involved_in

GO:0015970

guanosine tetraphosphate biosynthetic process

GO_REF:0000041

ECO:0000322

imported manually asserted information used in automatic assertion

UniPathway:UPA00908

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 1.3 1.4 1.5 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
  2. Metzger, S et al. (1989) Characterization of the relA1 mutation and a comparison of relA1 with new relA null alleles in Escherichia coli. J. Biol. Chem. 264 21146-52 PubMed GONUTS page
  3. Wendrich, TM et al. (2002) Dissection of the mechanism for the stringent factor RelA. Mol. Cell 10 779-88 PubMed GONUTS page
  4. Pedersen, FS & Kjeldgaard, NO (1977) Analysis of the relA gene product of Escherichia coli. Eur. J. Biochem. 76 91-7 PubMed GONUTS page