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ECOLI:RCSB

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Species (Taxon ID) Escherichia coli (strain K12). (83333)
Gene Name(s) rcsB (ECO:0000255 with HAMAP-Rule:MF_00981)
Protein Name(s) Transcriptional regulatory protein RcsB (ECO:0000255 with HAMAP-Rule:MF_00981)

Capsular synthesis regulator component B

External Links
UniProt P0DMC7
EMBL M28242
U00096
AP009048
S37760
PIR JV0068
RefSeq NP_416721.1
YP_490455.1
ProteinModelPortal P0DMC7
SMR P0DMC7
IntAct P0DMC7
EnsemblBacteria AAC75277
BAA16000
GeneID 12931885
947441
KEGG ecj:Y75_p2178
eco:b2217
EchoBASE EB0814
EcoGene EG10821
eggNOG COG2197
HOGENOM HOG000034813
KO K07687
OMA IEWVNIV
OrthoDB EOG69GZGV
PhylomeDB P0DMC7
Proteomes UP000000318
UP000000625
GO GO:0003677
GO:0003700
GO:0000160
GO:0006351
Gene3D 1.10.10.10
HAMAP MF_00981
InterPro IPR011006
IPR016032
IPR001789
IPR000792
IPR011991
Pfam PF00196
PF00072
PRINTS PR00038
SMART SM00421
SM00448
SUPFAM SSF46894
SSF52172
PROSITE PS00622
PS50043
PS50110

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0044011

single-species biofilm formation on inanimate substrate

PMID:14651646[1]

ECO:0000315

P

Fig. 1: RcsC is required for biofilm formation, the mutant was complemented with a plasmid containing the rcsC gene and another one that contained a mutation in the rcsC gene

complete
CACAO 2481

GO:0031346

positive regulation of cell projection organization

PMID:17644608[2]

ECO:0000315

P

Fig. 2: RcsB enhances piliation. The rcsB mutant has fewer pili in the TEM

complete
CACAO 2493

GO:0046677

response to antibiotic

PMID:18192383[3]

ECO:0000315

P

Fig 6.

complete
CACAO 2974

involved_in

GO:0046677

response to antibiotic

PMID:18192383[3]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0031346

positive regulation of cell projection organization

PMID:17644608[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0044011

single-species biofilm formation on inanimate substrate

PMID:14651646[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0045893

positive regulation of transcription, DNA-templated

PMID:3888955[4]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0045892

negative regulation of transcription, DNA-templated

PMID:12864862[5]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0006351

transcription, DNA-templated

PMID:12864862[5]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0006351

transcription, DNA-templated

PMID:10702265[6]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0006351

transcription, DNA-templated

PMID:9882673[7]

ECO:0000270

expression pattern evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0006351

transcription, DNA-templated

PMID:16000739[8]

ECO:0000270

expression pattern evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0005829

cytosol

PMID:18304323[9]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

enables

GO:0001217

DNA-binding transcription repressor activity

PMID:12864862[5]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0001216

DNA-binding transcription activator activity

PMID:15901715[10]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0000160

phosphorelay signal transduction system

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001789
InterPro:IPR030864

P

Seeded From UniProt

complete

enables

GO:0003677

DNA binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR016032

F

Seeded From UniProt

complete

involved_in

GO:0006355

regulation of transcription, DNA-templated

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000792
InterPro:IPR016032
InterPro:IPR030864

P

Seeded From UniProt

complete

involved_in

GO:0000160

phosphorelay signal transduction system

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000119457

P

Seeded From UniProt

complete

involved_in

GO:0006355

regulation of transcription, DNA-templated

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000119457

P

Seeded From UniProt

complete

enables

GO:0003677

DNA binding

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000119457

F

Seeded From UniProt

complete

involved_in

GO:0000160

phosphorelay signal transduction system

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0902

P

Seeded From UniProt

complete

enables

GO:0003677

DNA binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0238

F

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Ferrières, L & Clarke, DJ (2003) The RcsC sensor kinase is required for normal biofilm formation in Escherichia coli K-12 and controls the expression of a regulon in response to growth on a solid surface. Mol. Microbiol. 50 1665-82 PubMed GONUTS page
  2. 2.0 2.1 Schwan, WR et al. (2007) The two-component response regulator RcsB regulates type 1 piliation in Escherichia coli. J. Bacteriol. 189 7159-63 PubMed GONUTS page
  3. 3.0 3.1 Laubacher, ME & Ades, SE (2008) The Rcs phosphorelay is a cell envelope stress response activated by peptidoglycan stress and contributes to intrinsic antibiotic resistance. J. Bacteriol. 190 2065-74 PubMed GONUTS page
  4. Gottesman, S et al. (1985) Regulation of capsular polysaccharide synthesis in Escherichia coli K-12: characterization of three regulatory genes. J. Bacteriol. 162 1111-9 PubMed GONUTS page
  5. 5.0 5.1 5.2 Francez-Charlot, A et al. (2003) RcsCDB His-Asp phosphorelay system negatively regulates the flhDC operon in Escherichia coli. Mol. Microbiol. 49 823-32 PubMed GONUTS page
  6. Wehland, M & Bernhard, F (2000) The RcsAB box. Characterization of a new operator essential for the regulation of exopolysaccharide biosynthesis in enteric bacteria. J. Biol. Chem. 275 7013-20 PubMed GONUTS page
  7. Ebel, W & Trempy, JE (1999) Escherichia coli RcsA, a positive activator of colanic acid capsular polysaccharide synthesis, functions To activate its own expression. J. Bacteriol. 181 577-84 PubMed GONUTS page
  8. Vianney, A et al. (2005) Escherichia coli tol and rcs genes participate in the complex network affecting curli synthesis. Microbiology (Reading, Engl.) 151 2487-97 PubMed GONUTS page
  9. Ishihama, Y et al. (2008) Protein abundance profiling of the Escherichia coli cytosol. BMC Genomics 9 102 PubMed GONUTS page
  10. Francez-Charlot, A et al. (2005) Osmotic regulation of the Escherichia coli bdm (biofilm-dependent modulation) gene by the RcsCDB His-Asp phosphorelay. J. Bacteriol. 187 3873-7 PubMed GONUTS page