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ECOLI:PUR4

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Species (Taxon ID) Escherichia coli (strain K12). (83333)
Gene Name(s) purL (ECO:0000255 with HAMAP-Rule:MF_00419) (synonyms: purI)
Protein Name(s) Phosphoribosylformylglycinamidine synthase (ECO:0000255 with HAMAP-Rule:MF_00419)

FGAM synthase (ECO:0000255 with HAMAP-Rule:MF_00419) FGAMS (ECO:0000255 with HAMAP-Rule:MF_00419) Formylglycinamide ribonucleotide amidotransferase (ECO:0000255 with HAMAP-Rule:MF_00419) FGAR amidotransferase (ECO:0000255 with HAMAP-Rule:MF_00419) FGAR-AT (ECO:0000255 with HAMAP-Rule:MF_00419)

External Links
UniProt P15254
EMBL M19501
U36841
U00096
AP009048
PIR D65033
RefSeq YP_026170.1
YP_490785.1
ProteinModelPortal P15254
DIP DIP-10614N
IntAct P15254
MINT MINT-1262623
STRING 511145.b2557
MEROPS C56.972
PaxDb P15254
PRIDE P15254
EnsemblBacteria AAT48143
BAE76733
GeneID 12930212
947032
KEGG ecj:Y75_p2510
eco:b2557
PATRIC 32120513
EchoBASE EB0790
EcoGene EG10797
eggNOG COG0046
HOGENOM HOG000261359
InParanoid P15254
KO K01952
OMA TTVEPFN
OrthoDB EOG6FNHHR
PhylomeDB P15254
BioCyc EcoCyc:FGAMSYN-MONOMER
ECOL316407:JW2541-MONOMER
MetaCyc:FGAMSYN-MONOMER
UniPathway UPA00074
PRO PR:P15254
Proteomes UP000000318
UP000000625
Genevestigator P15254
GO GO:0005737
GO:0005524
GO:0042623
GO:0046872
GO:0004642
GO:0006189
GO:0006200
GO:0006541
Gene3D 3.30.1330.10
3.40.50.880
HAMAP MF_00419
InterPro IPR010918
IPR000728
IPR029062
IPR017926
IPR010073
IPR022940
IPR016188
Pfam PF00586
PF02769
SUPFAM SSF52317
SSF55326
SSF56042
TIGRFAMs TIGR01735
PROSITE PS51273

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

part_of

GO:0005737

cytoplasm

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

EcoGene:EG10797
PANTHER:PTN000010058

C

Seeded From UniProt

complete

enables

GO:0042623

ATPase activity, coupled

PMID:2659070[2]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0006541

glutamine metabolic process

PMID:2659070[2]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0006189

'de novo' IMP biosynthetic process

PMID:6343356[3]

ECO:0000305

curator inference used in manual assertion

GO:0004642

P

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

PMID:2659070[2]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

enables

GO:0005524

ATP binding

PMID:2659070[2]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0004642

phosphoribosylformylglycinamidine synthase activity

PMID:6343356[3]

ECO:0000315

mutant phenotype evidence used in manual assertion

F

Seeded From UniProt

complete

part_of

GO:0005829

cytosol

PMID:18304323[4]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

enables

GO:0004642

phosphoribosylformylglycinamidine synthase activity

PMID:2659070[2]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0004642

phosphoribosylformylglycinamidine synthase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR010073

F

Seeded From UniProt

complete

involved_in

GO:0006189

'de novo' IMP biosynthetic process

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR010073

P

Seeded From UniProt

complete

enables

GO:0004642

phosphoribosylformylglycinamidine synthase activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:6.3.5.3

F

Seeded From UniProt

complete

involved_in

GO:0006189

'de novo' IMP biosynthetic process

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000085142

P

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000085142

C

Seeded From UniProt

complete

enables

GO:0005524

ATP binding

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000085142

F

Seeded From UniProt

complete

enables

GO:0004642

phosphoribosylformylglycinamidine synthase activity

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000085142

F

Seeded From UniProt

complete

enables

GO:0000166

nucleotide binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0547

F

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0963
UniProtKB-SubCell:SL-0086

C

Seeded From UniProt

complete

involved_in

GO:0006541

glutamine metabolic process

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0315

P

Seeded From UniProt

complete

enables

GO:0046872

metal ion binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0479

F

Seeded From UniProt

complete

enables

GO:0005524

ATP binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0067

F

Seeded From UniProt

complete

involved_in

GO:0006164

purine nucleotide biosynthetic process

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0658

P

Seeded From UniProt

complete

enables

GO:0016874

ligase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0436

F

Seeded From UniProt

complete

involved_in

GO:0006189

'de novo' IMP biosynthetic process

GO_REF:0000041

ECO:0000322

imported manually asserted information used in automatic assertion

UniPathway:UPA00074

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 2.4 Schendel, FJ et al. (1989) Formylglycinamide ribonucleotide synthetase from Escherichia coli: cloning, sequencing, overproduction, isolation, and characterization. Biochemistry 28 2459-71 PubMed GONUTS page
  3. 3.0 3.1 Houlberg, U et al. (1983) Identification of the enzymatic reactions encoded by the purG and purI genes of Escherichia coli. J. Bacteriol. 154 1485-8 PubMed GONUTS page
  4. Ishihama, Y et al. (2008) Protein abundance profiling of the Escherichia coli cytosol. BMC Genomics 9 102 PubMed GONUTS page