GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.

Have any questions? Please email us at ecoliwiki@gmail.com

ECOLI:PRET

From GONUTS
Jump to: navigation, search
Species (Taxon ID) Escherichia coli (strain K12). (83333)
Gene Name(s) preT (synonyms: yeiT)
Protein Name(s) NAD-dependent dihydropyrimidine dehydrogenase subunit PreT

DPD Dihydrothymine dehydrogenase Dihydrouracil dehydrogenase

External Links
UniProt P76440
EMBL U00096
AP009048
PIR A64983
RefSeq NP_416651.1
YP_490385.1
ProteinModelPortal P76440
SMR P76440
DIP DIP-28055N
IntAct P76440
STRING 511145.b2146
EnsemblBacteria AAC75207
BAE76623
GeneID 12930175
949049
KEGG ecj:Y75_p2108
eco:b2146
PATRIC 32119635
EchoBASE EB3827
EcoGene EG14074
eggNOG COG0493
HOGENOM HOG000031439
InParanoid P76440
KO K17722
OMA HGPDIIH
OrthoDB EOG6XSZQF
PhylomeDB P76440
BioCyc EcoCyc:G7145-MONOMER
ECOL316407:JW2133-MONOMER
MetaCyc:G7145-MONOMER
PRO PR:P76440
Proteomes UP000000318
UP000000625
Genevestigator P76440
GO GO:0004159
GO:0050660
GO:0051536
GO:0003954
GO:0008152
GO:0006208
Gene3D 3.40.50.720
InterPro IPR028261
IPR009051
IPR016040
IPR023753
IPR001327
Pfam PF14691
PF00070
PF07992
SUPFAM SSF46548

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

involved_in

GO:0006208

pyrimidine nucleobase catabolic process

PMID:21169495[1]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0003954

NADH dehydrogenase activity

PMID:21169495[1]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0016491

oxidoreductase activity

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000234102
UniProtKB:Q74FU5

F

Seeded From UniProt

complete

enables

GO:0051536

iron-sulfur cluster binding

PMID:18482579[3]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0016491

oxidoreductase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR023753

F

Seeded From UniProt

complete

enables

GO:0051536

iron-sulfur cluster binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR009051

F

Seeded From UniProt

complete

involved_in

GO:0055114

oxidation-reduction process

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR023753

P

Seeded From UniProt

complete

enables

GO:0004159

dihydrouracil dehydrogenase (NAD+) activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:1.3.1.1

F

Seeded From UniProt

complete

involved_in

GO:0055114

oxidation-reduction process

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0560

P

Seeded From UniProt

complete

enables

GO:0016491

oxidoreductase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0560

F

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Hidese, R et al. (2011) Escherichia coli dihydropyrimidine dehydrogenase is a novel NAD-dependent heterotetramer essential for the production of 5,6-dihydrouracil. J. Bacteriol. 193 989-93 PubMed GONUTS page
  2. Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
  3. Mihara, H et al. (2008) The iscS gene deficiency affects the expression of pyrimidine metabolism genes. Biochem. Biophys. Res. Commun. 372 407-11 PubMed GONUTS page