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ECOLI:PGPB

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Species (Taxon ID) Escherichia coli (strain K12). (83333)
Gene Name(s) pgpB
Protein Name(s) Phosphatidylglycerophosphatase B

Diacylglycerol pyrophosphate phosphatase DGPP phosphatase Phosphatidate phosphatase Undecaprenyl pyrophosphate phosphatase Undecaprenyl-diphosphatase

External Links
UniProt P0A924
EMBL M23628
U00096
AP009048
PIR A30193
RefSeq NP_415794.1
YP_489546.1
ProteinModelPortal P0A924
SMR P0A924
IntAct P0A924
STRING 511145.b1278
EnsemblBacteria AAC74360
BAA14832
GeneID 12933201
945863
KEGG ecj:Y75_p1253
eco:b1278
PATRIC 32117818
EchoBASE EB0699
EcoGene EG10705
eggNOG COG0671
HOGENOM HOG000286191
InParanoid P0A924
KO K01096
OMA HTMFAAT
OrthoDB EOG60CWKV
BioCyc EcoCyc:PGPPHOSPHAB-MONOMER
ECOL316407:JW1270-MONOMER
MetaCyc:PGPPHOSPHAB-MONOMER
UniPathway UPA00084
PRO PR:P0A924
Proteomes UP000000318
UP000000625
Genevestigator P0A924
GO GO:0009279
GO:0005887
GO:0005886
GO:0000810
GO:0008195
GO:0008962
GO:0050380
GO:0016311
GO:0046474
GO:0009252
GO:0006655
GO:0009395
Gene3D 1.20.144.10
InterPro IPR000326
Pfam PF01569
SMART SM00014
SUPFAM SSF48317

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0008962

phosphatidylglycerophosphatase activity

PMID:1309518[1]

ECO:0000314

F

figure 2.

complete

enables

GO:0050380

undecaprenyl-diphosphatase activity

PMID:15778224[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0050380

undecaprenyl-diphosphatase activity

PMID:18411271[3]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0046474

glycerophospholipid biosynthetic process

PMID:6296050[4]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0009279

cell outer membrane

PMID:2846511[5]

ECO:0000315

mutant phenotype evidence used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0009252

peptidoglycan biosynthetic process

PMID:15778224[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0008962

phosphatidylglycerophosphatase activity

PMID:6296050[4]

ECO:0000315

mutant phenotype evidence used in manual assertion

F

Seeded From UniProt

complete

part_of

GO:0005887

integral component of plasma membrane

PMID:18411271[3]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

PMID:2846511[5]

ECO:0000315

mutant phenotype evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

PMID:17309111[6]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

PMID:15919996[7]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0016311

dephosphorylation

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0008962

P

Seeded From UniProt

complete

involved_in

GO:0016311

dephosphorylation

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0008962

P

Seeded From UniProt

complete

involved_in

GO:0016311

dephosphorylation

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0008195

P

Seeded From UniProt

complete

enables

GO:0008962

phosphatidylglycerophosphatase activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:3.1.3.27

F

Seeded From UniProt

complete

enables

GO:0050380

undecaprenyl-diphosphatase activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:3.6.1.27

F

Seeded From UniProt

complete

enables

GO:0008195

phosphatidate phosphatase activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:3.1.3.4

F

Seeded From UniProt

complete

enables

GO:0000810

diacylglycerol diphosphate phosphatase activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:3.1.3.81

F

Seeded From UniProt

complete

involved_in

GO:0016042

lipid catabolic process

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0442

P

Seeded From UniProt

complete

enables

GO:0016787

hydrolase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0378

F

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

GO_REF:0000037
GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-1003
UniProtKB-KW:KW-0997
UniProtKB-SubCell:SL-0037

C

Seeded From UniProt

complete

part_of

GO:0016021

integral component of membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0812

C

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0472

C

Seeded From UniProt

complete

involved_in

GO:0006629

lipid metabolic process

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0443

P

Seeded From UniProt

complete

involved_in

GO:0009395

phospholipid catabolic process

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0595

P

Seeded From UniProt

complete

part_of

GO:0009279

cell outer membrane

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0998
UniProtKB-SubCell:SL-0040

C

Seeded From UniProt

complete

involved_in

GO:0006655

phosphatidylglycerol biosynthetic process

GO_REF:0000041

ECO:0000322

imported manually asserted information used in automatic assertion

UniPathway:UPA00084

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Funk, CR et al. (1992) The pgpA and pgpB genes of Escherichia coli are not essential: evidence for a third phosphatidylglycerophosphate phosphatase. J. Bacteriol. 174 205-13 PubMed GONUTS page
  2. 2.0 2.1 El Ghachi, M et al. (2005) Identification of multiple genes encoding membrane proteins with undecaprenyl pyrophosphate phosphatase (UppP) activity in Escherichia coli. J. Biol. Chem. 280 18689-95 PubMed GONUTS page
  3. 3.0 3.1 Touzé, T et al. (2008) Substrate specificity and membrane topology of Escherichia coli PgpB, an undecaprenyl pyrophosphate phosphatase. J. Biol. Chem. 283 16573-83 PubMed GONUTS page
  4. 4.0 4.1 Icho, T & Raetz, CR (1983) Multiple genes for membrane-bound phosphatases in Escherichia coli and their action on phospholipid precursors. J. Bacteriol. 153 722-30 PubMed GONUTS page
  5. 5.0 5.1 Icho, T (1988) Membrane-bound phosphatases in Escherichia coli: sequence of the pgpB gene and dual subcellular localization of the pgpB product. J. Bacteriol. 170 5117-24 PubMed GONUTS page
  6. Zhang, N et al. (2007) Comparison of SDS- and methanol-assisted protein solubilization and digestion methods for Escherichia coli membrane proteome analysis by 2-D LC-MS/MS. Proteomics 7 484-93 PubMed GONUTS page
  7. Daley, DO et al. (2005) Global topology analysis of the Escherichia coli inner membrane proteome. Science 308 1321-3 PubMed GONUTS page