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ECOLI:PDXA
Contents
| Species (Taxon ID) | Escherichia coli (strain K12). (83333) | |
| Gene Name(s) | pdxA | |
| Protein Name(s) | 4-hydroxythreonine-4-phosphate dehydrogenase
4-(phosphohydroxy)-L-threonine dehydrogenase | |
| External Links | ||
| UniProt | P19624 | |
| EMBL | M68521 U00096 AP009048 | |
| PIR | JV0026 | |
| RefSeq | NP_414594.1 YP_488358.1 | |
| PDB | 1PS6 1PS7 1PTM | |
| PDBsum | 1PS6 1PS7 1PTM | |
| ProteinModelPortal | P19624 | |
| SMR | P19624 | |
| DIP | DIP-10448N | |
| IntAct | P19624 | |
| STRING | 511145.b0052 | |
| PaxDb | P19624 | |
| PRIDE | P19624 | |
| EnsemblBacteria | AAC73163 BAB96619 | |
| GeneID | 12932019 944919 | |
| KEGG | ecj:Y75_p0052 eco:b0052 | |
| PATRIC | 32115203 | |
| EchoBASE | EB0685 | |
| EcoGene | EG10691 | |
| eggNOG | COG1995 | |
| HOGENOM | HOG000221592 | |
| InParanoid | P19624 | |
| KO | K00097 | |
| OMA | DTLFQDK | |
| OrthoDB | EOG6GN6ZC | |
| PhylomeDB | P19624 | |
| BioCyc | EcoCyc:PDXA-MONOMER ECOL316407:JW0051-MONOMER MetaCyc:PDXA-MONOMER | |
| UniPathway | UPA00244 | |
| EvolutionaryTrace | P19624 | |
| PRO | PR:P19624 | |
| Proteomes | UP000000318 UP000000625 | |
| Genevestigator | P19624 | |
| GO | GO:0005737 GO:0050570 GO:0050897 GO:0042802 GO:0000287 GO:0051287 GO:0008270 GO:0042823 GO:0008615 | |
| Gene3D | 3.40.718.10 | |
| HAMAP | MF_00536 | |
| InterPro | IPR024084 IPR005255 | |
| Pfam | PF04166 | |
| TIGRFAMs | TIGR00557 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
|
enables |
GO:0042802 |
identical protein binding |
ECO:0000353 |
physical interaction evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0042802 |
identical protein binding |
ECO:0000353 |
physical interaction evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0051287 |
NAD binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0050570 |
4-hydroxythreonine-4-phosphate dehydrogenase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0042823 |
pyridoxal phosphate biosynthetic process |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0008615 |
pyridoxine biosynthetic process |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0008270 |
zinc ion binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0008270 |
zinc ion binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0000287 |
magnesium ion binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0042823 |
pyridoxal phosphate biosynthetic process |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0050570 |
4-hydroxythreonine-4-phosphate dehydrogenase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0051287 |
NAD binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0055114 |
oxidation-reduction process |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0050570 |
4-hydroxythreonine-4-phosphate dehydrogenase activity |
ECO:0000501 |
evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0042823 |
pyridoxal phosphate biosynthetic process |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000094090 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0008615 |
pyridoxine biosynthetic process |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000094090 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0008270 |
zinc ion binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000094090 |
F |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000094090 |
C |
Seeded From UniProt |
complete | ||
|
enables |
GO:0050570 |
4-hydroxythreonine-4-phosphate dehydrogenase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000094090 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0000287 |
magnesium ion binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000094090 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0046872 |
metal ion binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000094090 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0050897 |
cobalt ion binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000094090 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0046872 |
metal ion binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0055114 |
oxidation-reduction process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016491 |
oxidoreductase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0008615 |
pyridoxine biosynthetic process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Häuser, R et al. (2014) A second-generation protein-protein interaction network of Helicobacter pylori. Mol. Cell Proteomics 13 1318-29 PubMed GONUTS page
- ↑ Rajagopala, SV et al. (2014) The binary protein-protein interaction landscape of Escherichia coli. Nat. Biotechnol. 32 285-90 PubMed GONUTS page
- ↑ 3.0 3.1 Sivaraman, J et al. (2003) Crystal structure of Escherichia coli PdxA, an enzyme involved in the pyridoxal phosphate biosynthesis pathway. J. Biol. Chem. 278 43682-90 PubMed GONUTS page
- ↑ 4.0 4.1 4.2 Banks, J & Cane, DE (2004) Biosynthesis of vitamin B6: direct identification of the product of the PdxA-catalyzed oxidation of 4-hydroxy-l-threonine-4-phosphate using electrospray ionization mass spectrometry. Bioorg. Med. Chem. Lett. 14 1633-6 PubMed GONUTS page
- ↑ 5.0 5.1 Lam, HM et al. (1992) Suppression of insertions in the complex pdxJ operon of Escherichia coli K-12 by lon and other mutations. J. Bacteriol. 174 1554-67 PubMed GONUTS page
