GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.
ECOLI:PA1
Contents
| Species (Taxon ID) | Escherichia coli (strain K12). (83333) | |
| Gene Name(s) | pldA | |
| Protein Name(s) | Phospholipase A1
Detergent-resistant phospholipase A DR-phospholipase A Outer membrane phospholipase A OM PLA OMPLA Phosphatidylcholine 1-acylhydrolase | |
| External Links | ||
| UniProt | P0A921 | |
| EMBL | X02143 M87049 U00096 AP009048 M30198 | |
| PIR | A22133 | |
| RefSeq | NP_418265.1 YP_491621.1 | |
| PDB | 1FW2 1FW3 1ILD 1ILZ 1IM0 1QD5 1QD6 | |
| PDBsum | 1FW2 1FW3 1ILD 1ILZ 1IM0 1QD5 1QD6 | |
| ProteinModelPortal | P0A921 | |
| SMR | P0A921 | |
| IntAct | P0A921 | |
| STRING | 511145.b3821 | |
| PaxDb | P0A921 | |
| PRIDE | P0A921 | |
| EnsemblBacteria | AAC76824 BAE77480 | |
| GeneID | 12930309 948307 | |
| KEGG | ecj:Y75_p3357 eco:b3821 | |
| PATRIC | 32123143 | |
| EchoBASE | EB0731 | |
| EcoGene | EG10738 | |
| eggNOG | COG2829 | |
| HOGENOM | HOG000288150 | |
| InParanoid | P0A921 | |
| KO | K01058 | |
| OMA | YNHRQTR | |
| OrthoDB | EOG6HQSN6 | |
| PhylomeDB | P0A921 | |
| BioCyc | EcoCyc:MONOMER0-341 ECOL316407:JW3794-MONOMER MetaCyc:MONOMER0-341 | |
| EvolutionaryTrace | P0A921 | |
| PRO | PR:P0A921 | |
| Proteomes | UP000000318 UP000000625 | |
| Genevestigator | P0A921 | |
| GO | GO:0045203 GO:0031230 GO:0052740 GO:0005509 GO:0008970 GO:0052739 GO:0004623 GO:0042803 GO:0016042 | |
| Gene3D | 2.40.230.10 | |
| InterPro | IPR003187 | |
| Pfam | PF02253 | |
| PRINTS | PR01486 | |
| SUPFAM | SSF56931 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
| GO:0009279 |
cell outer membrane |
ECO:0000314 |
C |
Table 1 |
complete | |||||
|
enables |
GO:0042803 |
protein homodimerization activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0031230 |
intrinsic component of cell outer membrane |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0005509 |
calcium ion binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0045203 |
integral component of cell outer membrane |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
EcoGene:EG10738 |
C |
Seeded From UniProt |
complete | ||
|
enables |
GO:0005509 |
calcium ion binding |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
EcoGene:EG10738 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0004623 |
phospholipase A2 activity |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
EcoGene:EG10738 |
F |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0045203 |
integral component of cell outer membrane |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0009279 |
cell outer membrane |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0005509 |
calcium ion binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004623 |
phospholipase A2 activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004620 |
phospholipase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006629 |
lipid metabolic process |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016020 |
membrane |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0008970 |
phospholipase A1 activity |
ECO:0000501 |
evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0052740 |
1-acyl-2-lysophosphatidylserine acylhydrolase activity |
ECO:0000501 |
evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0102568 |
phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) |
ECO:0000501 |
evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0052739 |
phosphatidylserine 1-acylhydrolase activity |
ECO:0000501 |
evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004623 |
phospholipase A2 activity |
ECO:0000501 |
evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0102567 |
phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) |
ECO:0000501 |
evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0008970 |
phospholipase A1 activity |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004623 |
phospholipase A2 activity |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0016042 |
lipid catabolic process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006629 |
lipid metabolic process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016787 |
hydrolase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016020 |
membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0009279 |
cell outer membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0046872 |
metal ion binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016021 |
integral component of membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Molloy, MP et al. (2000) Proteomic analysis of the Escherichia coli outer membrane. Eur. J. Biochem. 267 2871-81 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 2.4 2.5 Snijder, HJ et al. (2001) Structural investigations of calcium binding and its role in activity and activation of outer membrane phospholipase A from Escherichia coli. J. Mol. Biol. 309 477-89 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
- ↑ Homma, H et al. (1984) Characteristics of detergent-resistant phospholipase A overproduced in E. coli cells bearing its cloned structural gene. J. Biochem. 96 1645-53 PubMed GONUTS page
- ↑ Horrevoets, AJ et al. (1989) Kinetic characterization of Escherichia coli outer membrane phospholipase A using mixed detergent-lipid micelles. Biochemistry 28 1139-47 PubMed GONUTS page
b
o
p
- GO:0052739 ! phosphatidylserine 1-acylhydrolase activity
- GO:0102567 ! phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine)
- GO:0102568 ! phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine)
- GO:0004620 ! phospholipase activity
- GO:0008970 ! phospholipase A1 activity
- GO:0004623 ! phospholipase A2 activity
- GO:0042803 ! protein homodimerization activity
- Proteobacteria
