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ECOLI:OBG
Contents
| Species (Taxon ID) | Escherichia coli (strain K12). (83333) | |
| Gene Name(s) | obgE (ECO:0000255 with HAMAP-Rule:MF_01454) (synonyms: cgtA, obg, yhbZ) | |
| Protein Name(s) | GTPase ObgE/CgtA (ECO:0000255 with HAMAP-Rule:MF_01454)
GTP-binding protein Obg (ECO:0000255 with HAMAP-Rule:MF_01454) | |
| External Links | ||
| UniProt | P42641 | |
| EMBL | U18997 U00096 AP009048 | |
| PIR | A65109 | |
| RefSeq | NP_417650.1 YP_491368.1 | |
| PDB | 4CSU | |
| PDBsum | 4CSU | |
| ProteinModelPortal | P42641 | |
| SMR | P42641 | |
| DIP | DIP-12273N | |
| IntAct | P42641 | |
| MINT | MINT-1234247 | |
| STRING | 511145.b3183 | |
| PaxDb | P42641 | |
| PRIDE | P42641 | |
| EnsemblBacteria | AAC76215 BAE77227 | |
| GeneID | 12932653 947694 | |
| KEGG | ecj:Y75_p3103 eco:b3183 | |
| PATRIC | 32121786 | |
| EchoBASE | EB2647 | |
| EcoGene | EG12795 | |
| eggNOG | COG0536 | |
| HOGENOM | HOG000019084 | |
| InParanoid | P42641 | |
| KO | K03979 | |
| OMA | RTKVLIH | |
| OrthoDB | EOG6H1Q1M | |
| PhylomeDB | P42641 | |
| BioCyc | EcoCyc:G7656-MONOMER ECOL316407:JW3150-MONOMER | |
| PRO | PR:P42641 | |
| Proteomes | UP000000318 UP000000625 | |
| Genevestigator | P42641 | |
| GO | GO:0005829 GO:0003677 GO:0019003 GO:0005525 GO:0003924 GO:0032561 GO:0000287 GO:0019843 GO:0007059 GO:0006184 GO:0042255 | |
| Gene3D | 2.70.210.12 3.40.50.300 | |
| HAMAP | MF_01454 | |
| InterPro | IPR014100 IPR006074 IPR006169 IPR006073 IPR027417 | |
| PANTHER | PTHR11702:SF3 | |
| Pfam | PF01018 PF01926 | |
| PIRSF | PIRSF002401 | |
| PRINTS | PR00326 | |
| SUPFAM | SSF52540 SSF82051 | |
| TIGRFAMs | TIGR02729 | |
| PROSITE | PS51710 PS00905 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
|
involved_in |
GO:0022611 |
dormancy process |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0090071 |
negative regulation of ribosome biogenesis |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0043023 |
ribosomal large subunit binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0042255 |
ribosome assembly |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0032561 |
guanyl ribonucleotide binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0019003 |
GDP binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0007059 |
chromosome segregation |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005829 |
cytosol |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005829 |
cytosol |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0005525 |
GTP binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003924 |
GTPase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0000287 |
magnesium ion binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003924 |
GTPase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0005525 |
GTP binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
InterPro:IPR006073 |
F |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000078165 |
C |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0042254 |
ribosome biogenesis |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000078165 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0003924 |
GTPase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000078165 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0005525 |
GTP binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000078165 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0003723 |
RNA binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0019843 |
rRNA binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016787 |
hydrolase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0000166 |
nucleotide binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0046872 |
metal ion binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003677 |
DNA binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0005525 |
GTP binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Verstraeten, N et al. (2015) Obg and Membrane Depolarization Are Part of a Microbial Bet-Hedging Strategy that Leads to Antibiotic Tolerance. Mol. Cell 59 9-21 PubMed GONUTS page
- ↑ 2.0 2.1 Feng, B et al. (2014) Structural and functional insights into the mode of action of a universally conserved Obg GTPase. PLoS Biol. 12 e1001866 PubMed GONUTS page
- ↑ Jiang, M et al. (2006) The Escherichia coli GTPase CgtAE is involved in late steps of large ribosome assembly. J. Bacteriol. 188 6757-70 PubMed GONUTS page
- ↑ Persky, NS et al. (2009) The ObgE/CgtA GTPase influences the stringent response to amino acid starvation in Escherichia coli. Mol. Microbiol. 73 253-66 PubMed GONUTS page
- ↑ 5.0 5.1 5.2 Kobayashi, G et al. (2001) Deficiency of essential GTP-binding protein ObgE in Escherichia coli inhibits chromosome partition. Mol. Microbiol. 41 1037-51 PubMed GONUTS page
- ↑ Foti, JJ et al. (2007) Chromosome segregation control by Escherichia coli ObgE GTPase. Mol. Microbiol. 65 569-81 PubMed GONUTS page
- ↑ Ishihama, Y et al. (2008) Protein abundance profiling of the Escherichia coli cytosol. BMC Genomics 9 102 PubMed GONUTS page
- ↑ Sato, A et al. (2005) The GTP binding protein Obg homolog ObgE is involved in ribosome maturation. Genes Cells 10 393-408 PubMed GONUTS page
